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Targeting ultra-processed foods for prevention of type 2 diabetes: state of the evidence and future directions.
Diabetologia
January 2025
Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
The incidence of type 2 diabetes has risen globally, in parallel with the obesity epidemic and environments promoting a sedentary lifestyle and low-quality diet. There has been scrutiny of ultra-processed foods (UPFs) as a driver of type 2 diabetes, underscored by their increasing availability and intake worldwide, across countries of all incomes. This narrative review addresses the accumulated evidence from investigations of the trends in UPF consumption and the relationship with type 2 diabetes incidence.
View Article and Find Full Text PDFInterventions supporting meaningful connections for people with serious mental illness: a concept-framed systematic narrative review.
Soc Psychiatry Psychiatr Epidemiol
January 2025
College of Education, Psychology and Social Work, Flinders University, Adelaide, Australia.
Purpose: Meaningful connections, encompassing relationships providing emotional support, understanding, acceptance, and a sense of belonging, are vital for social inclusion and well-being of Individuals with serious mental illness (SMI). The mixed methods review critically explored multifaceted approaches supporting people with SMI to foster meaningful (non-intimate) social relationships or connections.
Methods: Searches of eight electronic databases returned 4882 records.
Factors affecting utilization of male sexual and reproductive health services: a qualitative description of males in Anambra State, Southeast Nigeria.
BMC Public Health
January 2025
Department of Community Medicine, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria.
Introduction: The utilization of sexual and reproductive health (SRH) services by males globally is significantly low despite their considerable sexual and reproductive health needs. This study aimed to understand the factors that influence the utilization of male sexual and reproductive health SRH services.
Methods: We used an explanatory sequential mixed methods research design, with qualitative description to explore the perceptions of males (15-49years) on the utilization of male SRH services in Anambra State, Nigeria.
Metabolic syndrome and its effect on immune cells in apical periodontitis- a narrative review.
Clin Oral Investig
January 2025
Faculty of Dentistry, University of Toronto, 124 Edward Street, Toronto, ON, M5G 1G6, Canada.
Objectives: Apical periodontitis (AP) is an inflammatory immune response in periapical tissues caused by microbial infections. Failure of root canal treatment or delayed healing is often due to intracanal or extra-radicular bacteria. However, beyond microbial factors, the patient's systemic health can significantly influence the progression and healing of AP.
View Article and Find Full Text PDFExamining memory reconsolidation as a mechanism of nitrous oxide's antidepressant action.
Neuropsychopharmacology
January 2025
Department of Psychiatry, Oxford University, Warneford Hospital, Oxford, UK.
There is an ongoing need to identify novel pharmacological agents for the effective treatment of depression. One emerging candidate, which has demonstrated rapid-acting antidepressant effects in treatment-resistant groups, is nitrous oxide (NO)-a gas commonly used for sedation and pain management in clinical settings and with a range of pharmacological effects, including antagonism of NMDA glutamate receptors. A growing body of evidence suggests that subanaesthetic doses of NO (50%) can interfere with the reconsolidation of maladaptive memories in healthy participants and across a range of disorders.
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