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Major Adverse Kidney Events in Hospitalized Older Patients With Acute Kidney Injury: Machine Learning-Based Model Development and Validation Study.
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Department of Nephrology, Hunan Key Laboratory of Kidney Disease and Blood Purification, The Second Xiangya Hospital of Central South University, Changsha, China.
Background: Acute kidney injury (AKI) is a common complication in hospitalized older patients, associated with increased morbidity, mortality, and health care costs. Major adverse kidney events within 30 days (MAKE30), a composite of death, new renal replacement therapy, or persistent renal dysfunction, has been recommended as a patient-centered endpoint for clinical trials involving AKI.
Objective: This study aimed to develop and validate a machine learning-based model to predict MAKE30 in hospitalized older patients with AKI.
Professional Development Among African Oncologists: Examining Professional Development Activities, Satisfaction Levels, Barriers, and Enablers.
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Saint Michael's Hospital, University of Toronto, Toronto, Canada.
Africa is currently facing unprecedented growth in its cancer burden. Training an adequate number of skilled physicians is critical to addressing this challenge. We examine African oncology faculty's professional development (PD) activities, associated barriers, enablers, satisfaction levels, and highlight the implications for improving the quality of the oncology faculty workforce in SSA.
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Department of Pathology and Laboratory Medicine, UC Davis Health, Sacramento, CA, United States.
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View Article and Find Full Text PDFMind the Gap: A Neural Network Framework for Imputing Genotypes in Non-Model Species.
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Section for Molecular Ecology and Evolution, Globe Institute, University of Copenhagen, Copenhagen, Denmark.
Reduced representation sequencing (RRS) has proven to be a cost-effective solution for sequencing subsets of the genome in non-model species for large-scale studies. However, the targeted nature of RRS approaches commonly introduces large amounts of missing data, leading to reduced statistical power and biased estimates in downstream analyses. Genotype imputation, the statistical inference of missing sites across the genome, is a powerful alternative to overcome the caveats associated with missing sites.
View Article and Find Full Text PDFEfficient Alkaline-Free Electrooxidation of 5-Hydroxymethylfurfural to 2,5-Furandicarboxylic Acid using Electrochemically-Charged NixCo1-x(OH)2 as a Redox Mediator.
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Griffith University, Griffith School of Environment, Centre for Clean Environment and Energy, 4222, Brisbane, AUSTRALIA.
Converting biomass-derived molecules like 5-hydroxymethylfurfural (HMF) into value-added products alongside hydrogen production using renewable energy offers significant opportunities for sustainable chemical and energy production. Yet, HMF electrooxidation requires strong alkaline conditions and membranes for efficient conversion. These harsh conditions destabilize HMF, leading to humin formation and reduced product purity, meanwhile membranes increase costs.
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