Dermatofibroma (DF) is a common, benign fibrohistiocytic tumor with unknown pathogenesis. There are multiple uncommon histologic variants of DF reported in literature, one of which is hemosiderotic DF. It can variably present as a pigmented papule or nodule commonly located on the lower extremities. Hemosiderotic DF remains to be underreported in the Philippines despite the widely available dermatopathology services in the country.
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| http://dx.doi.org/10.47895/amp.v58i17.8194 | DOI Listing |
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Hemosiderotic Dermatofibroma in a Filipino Male.
Acta Med Philipp
September 2024
Department of Dermatology, Philippine General Hospital, University of the Philippines Manila.
Dermatofibroma (DF) is a common, benign fibrohistiocytic tumor with unknown pathogenesis. There are multiple uncommon histologic variants of DF reported in literature, one of which is hemosiderotic DF. It can variably present as a pigmented papule or nodule commonly located on the lower extremities.
View Article and Find Full Text PDFGiant thigh hemosiderotic/aneurysmal dermatofibroma: Case report with radiologic-pathologic correlation.
Rev Esp Patol
July 2024
Príncipe de Asturias University Hospital, Pathology Department, Spain.
Article Synopsis
- Hemosiderotic/aneurysmal variant of dermatofibroma is a rare type of skin tumor that can be misdiagnosed as malignant cancers, such as melanomas or sarcomas.
- The report details a case of a 7.6cm subcutaneous tumor in a 53-year-old woman, highlighting its unique imaging characteristics and histological features, including the presence of hemosiderin pigment and pseudovascular spaces.
- Despite the tumor being large and not having clear surgical margins, the patient showed no signs of local recurrence or metastasis after its removal.
168 Cases of aneurysmal dermatofibroma and 29 cases of hemosiderotic dermatofibroma: A clinicopathologic study.
Am J Clin Pathol
March 2024
Dermatology, Nippon Medical School Musashi-Kosugi Hospital, Kanagawa, Japan.
Objectives: Aneurysmal dermatofibroma (ADF) and hemosiderotic dermatofibroma (HDF) are rare variants of dermatofibroma (DF) characterized by distinct histologic features. While HDF is traditionally considered a precursor to ADF, supporting evidence is limited, and the etiology remains unclear. A retrospective analysis of 2128 DF cases (2016-2019) was conducted to investigate the clinicopathologic characteristics of ADF, HDF, and other DFs.
View Article and Find Full Text PDFGiant Hemosiderotic Adenodermatofibroma: A Case Report and Review of the Literature.
Am J Dermatopathol
March 2023
Cleveland Clinic, Plastic Surgery and Dermatology Institute, Department of Dermatology, Cleveland, OH.
Adenodermatofibromas are an extremely rare subtype of dermatofibroma (DF) characterized by a dermal proliferation of spindle-shaped fibroblasts and histocytes, dilated glandular structures with apocrine secretion, and prominent vascular proliferation, with or without hemosiderotic features. We describe a recent extraordinary case of a hemosiderotic adenodermatofibroma in a 25-year-old female. We review histologic findings and theories behind etiology, as well as review the spectrum of clinical presentations for this lesion.
View Article and Find Full Text PDFHemosiderotic dermatofibroma (HDF) often mimics melanoma clinically. A definite diagnosis relies on histopathological evaluation and immunohistochemistry. As it can progress to aneurysmal dermatofibroma (ADF), complete excision is recommended.
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