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http://dx.doi.org/10.1016/j.jdcr.2024.06.024 | DOI Listing |
Microorganisms
November 2024
Departamento de Sanidad Vegetal, Facultad de Ciencias Agronómicas, Universidad de Chile, Santiago 8820808, Chile.
The wood decay fungi and severely threaten the worldwide cultivation of sweet cherry trees ( L.). Both fungi cause similar symptoms, including vascular necrosis, which leads to branch and twig dieback.
View Article and Find Full Text PDFPharmaceuticals (Basel)
December 2024
Department of Physiology, University of Louisville School of Medicine, Louisville, KY 40202, USA.
Late-onset Alzheimer's disease (LOAD) is a chronic, multifactorial, and progressive neurodegenerative disease that associates with aging and is highly prevalent in our older population (≥65 years of age). This hypothesis generating this narrative review will examine the important role for the use of sodium thiosulfate (STS) as a possible multi-targeting treatment option for LOAD. Sulfur is widely available in our environment and is responsible for forming organosulfur compounds that are known to be associated with a wide range of biological activities in the brain.
View Article and Find Full Text PDFInt J Mol Sci
December 2024
Division of Metabolism, Department of Internal Medicine, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.
Diabetic sensorimotor neuropathy (DSPN) is strongly associated with the extent of cellular oxidative stress and endothelial dysfunction in type 2 diabetes (T2DM). Alpha-lipoic acid (ALA) attenuates the progression of DSPN through its antioxidant and vasculoprotective effects. Kallistatin has antioxidant and anti-inflammatory properties.
View Article and Find Full Text PDFJ Clin Med
December 2024
Department of Pediatrics, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Pulmonary abscess is a rare but serious condition in pediatric patients, caused by severe pulmonary infection that leads to tissue destruction and necrosis. It can be classified as primary or secondary depending on the cause. Establishing an etiology in pediatric pulmonary abscesses is challenging, underscoring the essential role of advanced imaging techniques, such as computed tomography, in achieving an accurate diagnosis and differentiating among various conditions that may mimic lung abscess.
View Article and Find Full Text PDFBiomedicines
December 2024
Department of Orthopedics Surgery, Renmin Hospital of Wuhan University, Wuhan 430060, China.
Background: Glucocorticoids (GCs) are critical regulatory molecules in the body, commonly utilized in clinical practice for their potent anti-inflammatory and immunosuppressive properties. However, prolonged, high-dose GC therapy is frequently associated with femoral head necrosis, a condition known as glucocorticoid-induced osteonecrosis of the femoral head (GC-ONFH). Emerging evidence suggests that enhanced autophagy may mitigate apoptosis, thereby protecting osteoblasts from GC-induced damage and delaying the progression of ONFH.
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