Hemifacial Spasm is a neurological disorder characterized by persistent and rhythmic spasms of the facial muscles, significantly affecting the patient's quality of life. This condition can be classified into primary and secondary types; this article focuses on the characteristics of primary hemifacial spasm. Epidemiological studies indicate that the condition is more common in women, older adults, and individuals with posterior fossa stenosis or uneven blood flow dynamics, and is associated with gene expression related to demyelinating lesions. In terms of diagnosis, magnetic resonance imaging can show the location of arterial or venous compression on the facial nerve on a macroscopic level and reveal white matter lesions on a microscopic level. Additionally, optimized electrophysiological techniques can determine the type of neural excitation disorder from both central and peripheral perspectives, thereby improving detection rates. There are numerous treatment options available. Although early oral medications may have limited effectiveness, botulinum toxin injections can provide temporary relief. Future considerations include balancing injection costs with long-term efficacy. Microvascular decompression remains the preferred treatment approach and can be further optimized with endoscopic techniques. For refractory cases, alternative therapies such as facial nerve massage, radiofrequency techniques, rhizotomy, or acupuncture may be considered.
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http://dx.doi.org/10.1016/j.heliyon.2024.e38600 | DOI Listing |
Acta Neurochir (Wien)
January 2025
Department of Neurosurgery, University Medicine Greifswald, Greifswald, Germany.
Purpose: Currently available grading and classification systems for hemifacial spasm either rely on subjective assessments or are excessively intricate. Here, we make use of facial recognition and facial tracking technologies towards accurately grouping patients according to severity and characteristics of the spasms.
Methods: A retrospective review of our prospectively maintained preoperative videos database for hemifacial spasm was done.
NMC Case Rep J
December 2024
Department of Neurosurgery, Tokyo Medical and Dental University, Tokyo, Japan.
Hemifacial spasm (HFS) is a disorder that causes involuntary movements of the ipsilateral facial muscles because of vascular compression of the facial nerve. Microvascular decompression (MVD), a surgical procedure to detach the culprit vessel from the nerve is believed to be the most effective treatment for HFS. Nevertheless, in the rare case in which the vessel penetrates the nerve, positioning the vessel sufficiently far from the nerve is challenging.
View Article and Find Full Text PDFNeurophysiol Clin
December 2024
Department of Neurosurgery, Xinhua Hospital, Shanghai Jiaotong University, School of Medicine, The Cranial Nerve Disease Center of Shanghai Jiaotong University, 1665 Kongjiang Road, Shanghai 200092, China. Electronic address:
Objective: The aims of this study were to investigate the electrophysiological features of hemifacial spasm (HFS) and post-facial paralysis synkinesis (PFPS) that contribute to differential diagnosis.
Methods: This study was designed as a retrospective analysis, focusing on 132 patients diagnosed with HFS and 78 patients with PFPS between May and October 2023. Patient data were collected from existing medical records.
Neurol Sci
December 2024
Department of Neurology, Section of Clinical Neurophysiology, Faculty of Medicine, Gazi University, Ankara, Turkey.
Background: There is growing evidence that botulinum neurotoxin (BoNT) can mediate changes at the central level through peripheral mechanisms, leading to alterations in central sensorimotor integration. However, the effect of BoNT on brainstem excitability in patients with hemifacial spasm(HFS) is not yet fully understood, and its long-term effects remain unknown.
Objective: This study aims to investigate the impact of BoNT on the excitability of the facial nucleus in patients with idiopathic HFS.
Mov Disord Clin Pract
December 2024
Krembil Research Institute, University Health Network, University of Toronto, Toronto, Ontario, Canada.
Background: Myoclonus and other jerky movement disorders are hyperkinetic disorders, the diagnosis of which heavily relies on clinical neurophysiological testing. However, formal diagnostic criteria are lacking, and recently the utility and reliability of these tests have been questioned.
Objective: The aim of this review was to assess the utilization of clinical neurophysiology testing to identify possible gaps and boundaries that might guide the development of new methods for a more precise diagnosis and in-depth understanding of myoclonus.
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