Recent technological advancements and the advent of ever-growing databases in health care have fueled the emergence of "big data" analytics. Big data has the potential to revolutionize health care, particularly ophthalmology, given the data-intensive nature of the medical specialty. As one of the leading causes of irreversible blindness worldwide, glaucoma is an ocular disease that receives significant interest for developing innovations in eye care. Among the most vital sources of data in glaucoma is visual field (VF) testing, which stands as a cornerstone for diagnosing and managing the disease. The expanding accessibility of large VF databases has led to a surge in studies investigating various applications of big data analytics in glaucoma. In this study, we review the use of big data for evaluating the reliability of VF tests, gaining insights into real-world clinical practices and outcomes, understanding new disease associations and risk factors, characterizing the patterns of VF loss, defining the structure-function relationship of glaucoma, enhancing early diagnosis or earlier detection of progression, informing clinical decisions, and improving clinical trials. Equally important, we discuss current challenges in big data analytics and future directions for improvement.
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http://dx.doi.org/10.4103/tjo.TJO-D-24-00059 | DOI Listing |
BMJ Oncol
September 2023
Department of Big Data in Health Science, School of Public Health and The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Objective: This study aimed to explore the global burden of early-onset cancer based on the Global Burden of Disease (GBD) 2019 study for 29 cancers worldwid.
Methods And Analysis: Incidence, deaths, disability-adjusted life years (DALYs) and risk factors for 29 early-onset cancer groups were obtained from GBD.
Results: Global incidence of early-onset cancer increased by 79.
JACC Asia
January 2025
Division of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Background: Patients with end-stage renal disease (ESRD) are at a higher risk of cardiovascular diseases. Intravascular imaging (IVI)-guided percutaneous coronary intervention (PCI) using optical coherence tomography (OCT) or intravascular ultrasound (IVUS) has been shown to result in better clinical outcomes than angiography guidance. Nevertheless, the clinical outcomes of IVI-guided PCI in ESRD patients remain uncertain.
View Article and Find Full Text PDFBMJ Oncol
July 2024
National Institute for Data Science in Health and Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
Objective: To develop and validate machine-learning models that predict the risk of pan-cancer incidence using demographic, questionnaire and routine health check-up data in a large Asian population.
Methods And Analysis: This study is a prospective cohort study including 433 549 participants from the prospective MJ cohort including a male cohort (n=208 599) and a female cohort (n=224 950).
Results: During an 8-year median follow-up, 5143 cancers occurred in males and 4764 in females.
Front Artif Intell
January 2025
Independent Researcher, Hamburg, Germany.
Introduction: Artificial Intelligence (AI) is a transformative technology impacting various sectors of society and the economy. Understanding the factors influencing AI adoption is critical for both research and practice. This study focuses on two key objectives: (1) validating an extended version of the Technology Acceptance Model (TAM) in the context of AI by integrating the Big Five personality traits and AI mindset, and (2) conducting an exploratory k-prototype analysis to classify AI adopters based on demographics, AI-related attitudes, and usage patterns.
View Article and Find Full Text PDFPeerJ
January 2025
Department of Population and Public Health Sciences, University of Southern California, Los Angeles, California, United States.
Motivation: As data sets increase in size and complexity with advancing technology, flexible and interpretable data reduction methods that quantify information preservation become increasingly important.
Results: Super Partition is a large-scale approximation of the original Partition data reduction algorithm that allows the user to flexibly specify the minimum amount of information captured for each input feature. In an initial step, Genie, a fast, hierarchical clustering algorithm, forms a super-partition, thereby increasing the computational tractability by allowing Partition to be applied to the subsets.
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