Eosinophilic fasciitis (EF), or Shulman syndrome, is a rare connective tissue disorder characterized by symmetrical and painful swelling and with progressive thickening of the skin and soft tissues with the potential involvement of internal organs such as the pleura, pericardium, and kidneys. Patients may also present with fever, myositis, arthritis, neuropathies, and other systemic symptoms. This case report describes a unique multifocal asynchronous soft tissue involvement in Shulman syndrome in a 39-year-old patient, highlighting clinical presentation, histopathological findings, differential diagnoses, treatment modalities, and patient outcomes. Atypical migratory skin lesions must be considered in the diagnosis of EF. Timely recognition of the disease is crucial for optimal treatment and better patient outcomes.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11491105 | PMC |
http://dx.doi.org/10.7759/cureus.69801 | DOI Listing |
ACR Open Rheumatol
January 2025
Shanghai Sixth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
ARP Rheumatol
January 2024
Unidade Local de Saúde do Alto Minho.
Eur J Nucl Med Mol Imaging
December 2024
Nuclear Medicine Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Dermatol Reports
November 2024
Department of Dermatology, San Bortolo Hospital, Vicenza, Italy.
Eosinophilic fasciitis (EF) poses a diagnostic challenge owing to its uncommon occurrence and aetiology that remains poorly understood. We report a case of a 79-year-old woman with a prolonged history of breast cancer exhibiting EF with concomitant pelvic metastases. This case underscores EF's potential as an indicator signaling a potential resurgence of cancer, highlighting its significance as a red flag of disease recurrence.
View Article and Find Full Text PDFA 61 year old male presented with clinical signs of Eosinophilic fasciitis (EF), a rare connective tissue disease. Early recognition of the diagnosis of EF is essential. Common examination findings are prayer sign and distal limb swelling, induration, venous guttering, and peau d'orange.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!