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Diagnosis and management of subungual and periungual verruca: A clinical review.
J Am Acad Dermatol
November 2024
Department of Dermatology, Weill Cornell Medicine, New York, New York. Electronic address:
Nail unit verruca is the most common nail tumor encountered in clinical practice and may be highly distressing to patients due to reduced functionality, cosmesis, and stigmatization. Subungual and periungual verrucae present a challenge for treatment compared to cutaneous warts of other sites and recurrence rates are high. The risk of spread to other skin and mucosal areas inherent to all warts may be increased given location on the fingertips.
View Article and Find Full Text PDFArchaeology, ethnography, and geosciences reveal central role of traditional lifeways in shaping Madagascar's dry forests.
J Soc Archaeol
October 2024
Columbia Climate School, Columbia University, New York, NY, USA; Division of Biology and Paleoenvironment, Lamont Doherty Earth Observatory, Palisades, NY, USA; Columbia Center for Archaeology, Columbia University, New York, NY, USA.
Many communities in southwestern Madagascar rely on a mix of foraging, fishing, farming, and herding, with cattle central to local cultures, rituals, and intergenerational wealth transfer. Today these livelihoods are critically threatened by the intensifying effects of climate change and biodiversity loss. Improved understanding of ancient community-environment dynamics can help identify pathways to livelihood sustainability.
View Article and Find Full Text PDFThe Legacy of Pierre Paul Broca: A Bicentennial Celebration.
Neurol India
September 2024
Consultant Neurosurgeon, Former Professor of Neurosurgery, Former Vice Chancellor, University of Kerala, Thiruvananthapuram, Kerala, India.
Immunotherapy response and resistance in patients with advanced uveal melanoma: a retrospective cohort study.
Clin Exp Med
October 2024
Department of Dermatology, University Hospital of Zurich, University of Zurich, Raemistrasse 100, 8091, Zurich, Switzerland.
Metastatic uveal melanoma (mUM) is associated with poor prognosis. Ipilimumab/nivolumab has shown antitumor efficacy in phase II studies. Tebentafusp resulted in longer overall survival (OS) compared to investigator`s choice in a phase III study.
View Article and Find Full Text PDFTargeted radionuclide therapy for patients with central nervous system metastasis: Overlooked potential?
Neuro Oncol
December 2024
Department of Neurology, Clinical Neuroscience Center, University Hospital and University of Zurich, Zurich, Switzerland.
Article Synopsis
- Targeted radionuclide therapy is a new treatment option for metastatic cancer that uses nuclear medicine to identify and target tumors based on specific markers.
- This therapy can complement traditional radiotherapy, especially when imaging techniques like MRI miss microscopic metastases.
- Current approved uses include treating certain thyroid and prostate cancers, while ongoing research is exploring additional targets, with potential effectiveness against brain metastases if the necessary targets are present.
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