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SMARCB1/INI-1-Deficient sinonasal carcinoma demonstrates a poor prognosis but favorable clinical outcomes after PD-1/PD-L1 inhibitor therapy: A case series.
Sci Prog
January 2025
Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Despite advances in multimodal cancer therapy, such as combining radical surgery with high-intensity chemoradiotherapy, for SMARCB1/INI-1-deficient sinonasal carcinoma (SDSC), the prognosis of patients remains poor. Immunotherapy is gaining increasing popularity as a novel treatment strategy for patients with SMARCB1/INI-1-deficient tumors. Herein, we report on the management of three patients with SDSC who received PD-1/PD-L1 inhibitor therapy as a part of multimodal therapy based on surgery and chemoradiotherapy.
View Article and Find Full Text PDFFamily-led mid-upper arm circumference (FL-MUAC) approach and the screening of acute malnutrition in children aged 6 to 59 months in Africa: a scoping review.
Pan Afr Med J
January 2025
Department of Nutrition, Dietetics and Food Sciences, University of Zimbabwe, P.O Box MP 167, Mt Pleasant, Harare, Zimbabwe.
family-led mid-upper arm circumference (FL-MUAC) is a community-based acute malnutrition screening approach that is centered on training the mother or caregiver to use colour-coded MUAC tapes to screen children for malnutrition. A scoping review was conducted to summarise available evidence and evaluate the use of the FL-MUAC approach in the screening for acute malnutrition in Africa. A systematic literature search was performed using electronic databases to identify relevant research documents investigating the FL-MUAC approach.
View Article and Find Full Text PDFNational Patient Satisfaction Survey as a Predictor for Quality of Care and Quality Improvement - Experience and Practice.
Patient Prefer Adherence
January 2025
College of Public Health, Medical and Veterinary Sciences, James Cook University, Townsville, Queensland, Australia.
Background: Patient satisfaction is an important predictor of quality of care and hospital services. Patient satisfaction survey provides not only valuable insight into patient experience of care but also evidence that guides quality improvement in both system and organization levels. The paper aims to prove the value of system-wide satisfaction survey of patients and demonstrate whether data collected from a national patient satisfaction survey in three-year period can predict trends in patient experience of care.
View Article and Find Full Text PDFExamining the associations between social support and postpartum depression symptoms among adolescent mothers in Nairobi, Kenya.
Reprod Health
January 2025
Sexual, Reproductive, Maternal, Newborn, Child and Adolescent Health (SRMNCAH) Unit, African Population and Health Research Center, Nairobi, Kenya.
Background: Globally, adolescent mothers are at increased risk for postpartum depression (PPD). In Kenya, 15% of adolescent girls become mothers before the age of 18. While social support can buffer a mother's risk of PPD, there are gaps in knowledge as to whether-and which types-of social support are protective for adolescent mothers in Kenya.
View Article and Find Full Text PDFAntenatal care visits and its determinants among women in Afar regional state: North Eastern Ethiopia.
BMC Health Serv Res
January 2025
Department of Statistics, College of Natural and Computational Sciences, Samara University, Semera, Ethiopia.
Background: Antenatal care is an essential component of maternal healthcare that plays a crucial role in promoting the health and well-being of both mother and baby. While previous studies have examined factors influencing antenatal care visits in other parts of Ethiopia, there is a lack of research specifically focusing on the Afar region. This study aimed to assess determinants of antenatal care visits among pregnant women in Afar region, Ethiopia.
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