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Impact of Topical Tranexamic Acid on Bleeding Control in Rhinoplasty.
World J Plast Surg
January 2024
Anesthesiology and Critical Care Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Background: Hemorrhage during rhinoplasty may impair the surgeon's visibility. Our objective was to examine the impact of subcutaneously administered Tranexamic acid (TXA) on bleeding during rhinoplasty.
Methods: A three-blind randomized clinical trial including 60 patients undergoing nose surgery was conducted to compare the effects of two different anesthetic solutions on surgery results.
The efficacy and application of tranexamic acid in emergency medicine: Emergency Medicine Association of Türkiye clinical policy- 2024.
Turk J Emerg Med
October 2024
Department of Medical Education, Acibadem Mehmet Ali Aydınlar University, School of Medicine, Istanbul, Türkiye.
The clinical policy of the Emergency Medicine Association of Türkiye (EMAT) provides guidance on the use of tranexamic acid (TXA) in emergency settings. TXA, an antifibrinolytic drug, is used to control bleeding by inhibiting plasminogen. Its applications have expanded from hemophilia and severe menstrual bleeding to include various forms of trauma and surgery-related bleeding.
View Article and Find Full Text PDFIs Tranexamic Acid Safe for Patients Who Have End-Stage Renal Disease Undergoing Total Joint Arthroplasty?
J Arthroplasty
November 2024
Department of Orthopedic Surgery, NYU Langone Health, New York, New York.
Article Synopsis
- Tranexamic acid (TXA) is often used in total joint surgeries to reduce bleeding, but its effects on kidney function in end-stage renal disease (ESRD) patients were investigated in this study.
- A retrospective review of 123 ESRD patients undergoing knee and hip surgeries showed no significant differences in kidney function (measured by creatinine levels) or post-operative complications between those who received TXA and those who did not.
- The study concluded that TXA did not impact kidney function or the rates of emergency visits, readmissions, or mortality within 90 days post-surgery, indicating it may be safe for ESRD patients undergoing these procedures.
The Effects of Systemic Tranexamic Acid Administration on Drainage Volume, Duration of Drain Placement, and Length of Hospital Stay in Skin- and Nipple-Sparing Mastectomies with Immediate Expander-Based Breast Reconstruction.
J Clin Med
October 2024
Faculty of Biomedical Sciences, Università della Svizzera Italiana, CH-6900 Lugano, Switzerland.
: Skin- (SSM) and nipple-sparing (NSM) mastectomies are frequently performed surgeries with a considerable risk for post-operative hematoma or seroma. Tranexamic acid (TXA) is a potent antifibrinolytic drug commonly used in many surgical fields but rather novel in plastic and, specifically, breast surgery. This study investigates the influence of TXA in patients undergoing SSM or NSM with expander-based reconstruction (EbR) on post-operative outcomes.
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