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Predictive performance of ROX index and its variations for NIV failure.
Med Intensiva (Engl Ed)
January 2025
Department of Intensive Care Medicine, Laboratory for Critical Care Computational Intelligence, Amsterdam Medical Data Science, Amsterdam Public Health, Amsterdam Cardiovascular Science, Amsterdam Institute for Infection and Immunity, Amsterdam UMC, University of Amsterdam, Vrije Universiteit, Amsterdam, The Netherlands.
Objective: To determine whether the ROX index and its variations can predict the risk of intubation in ICU patients receiving NIV ventilation using large public ICU databases.
Design: Retrospective observational cohort study.
Setting: Patient data was extracted from both the AmsterdamUMCdb and the MIMIC-IV ICU databases, which contained data related to 20,109 and 50,920 unique patients.
A pilot study for continuous non-invasive intracranial pressure screening.
Comput Biol Med
January 2025
Servicio de Terapia Intensiva de Adultos, Hospital Italiano de Buenos Aires, Tte. Gral. Juan Domingo Perón 4190, Ciudad Autonoma de Buenos Aires, C1199ACL, Argentina.
Intracranial hypertension (ICH) is a common and critical condition in neurocritical care, often requiring immediate intervention. Current methods for continuous intracranial pressure (ICP) monitoring are invasive and costly, limiting their use in resource-limited settings. This study investigates the potential of the electroencephalography (EEG) as a non-invasive alternative for ICP monitoring.
View Article and Find Full Text PDFEnhanced Pneumonia Detection in Chest X-Rays Using Hybrid Convolutional and Vision Transformer Networks.
Curr Med Imaging
January 2025
School of Life Sciences, Tiangong University, Tianjin 300387, China.
Objective: The objective of this research is to enhance pneumonia detection in chest X-rays by leveraging a novel hybrid deep learning model that combines Convolutional Neural Networks (CNNs) with modified Swin Transformer blocks. This study aims to significantly improve diagnostic accuracy, reduce misclassifications, and provide a robust, deployable solution for underdeveloped regions where access to conventional diagnostics and treatment is limited.
Methods: The study developed a hybrid model architecture integrating CNNs with modified Swin Transformer blocks to work seamlessly within the same model.
Liquid Biopsy for Spinal Tumors: On the Frontiers of Clinical Application.
Global Spine J
January 2025
Combined Neurosurgical and Orthopedic Spine Program, Department of Orthopedics Surgery, University of British Columbia, Vancouver, BC, Canada.
Study Design: Narrative review.
Objectives: This article aims to provide a narrative review of the current state of research for liquid biopsy in spinal tumors and to discuss the potential application of liquid biopsy in the clinical management of patients with spinal tumors.
Methods: A comprehensive review of the literature was performed using PubMed, Google Scholar, Medline, Embase and Cochrane databases, and the review was limited to articles of English language.
Pragmatic algorithm for visual assessment of 4-Repeat tauopathies in [F]PI-2620 PET Scans.
Neuroimage
January 2025
Department of Nuclear Medicine, University Hospital, LMU Munich, Munich, Germany; German Center for Neurodegenerative Diseases (DZNE) Munich, Munich, Germany. Electronic address:
Aim: Standardized evaluation of [F]PI-2620 tau-PET scans in 4R-tauopathies represents an unmet need in clinical practice. This study aims to investigate the effectiveness of visual evaluation of [F]PI-2620 images for diagnosing 4R-tauopathies and to develop a straight-forward reading algorithm to improve objectivity and data reproducibility.
Methods: A total of 83 individuals with [F]PI-2620 PET scans were included.
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