The strategies for demixing and sorting mixed-chirality particles are crucial in the biochemical and pharmaceutical industries. However, whether chiral mixed particles can effectively separate in more complex spatial environments remains unresolved. In this paper, we explore the collective motion of binary chiral particle mixtures with environmental complex noise in the binary chiral Vicsek model (BCVM). We discover that the noisy region ratio, λ, significantly influences the separation behavior and spatial distribution of binary mixtures, unveiling system states not observed in uniform environments. Additionally, varying the chirality of particles reveals four distinct phases in our model. In the Vicsek bands phase (small chirality), an increase in λ can, under certain conditions, promote segregation rather than consistently hindering the demixing process. Conversely, for large chirality, localized dynamics and a homogeneous phase emerge, reducing the impact of λ on separation behavior. Notably, when chirality and activity are comparable, macrodrops and microflock phases appear, with a mixed-segregated state transition occurring at a critical λ_{c}. For λ<λ_{c}, chiral separation occurs with particles confined to the noise-free region. However, when λ>λ_{c}, particles gradually migrate to the noisy region, disrupting the separation. Further, we discuss the effects of multiple factors, including chirality, velocity, noise magnitude, particle number, and system size on λ_{c}. We also identify an optimal interaction radius at which λ_{c} reaches its peak value. Our findings may inspire strategies for achieving spontaneous demixing and spatial migration of mixed-chirality particles in complex environments.
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http://dx.doi.org/10.1103/PhysRevE.110.034135 | DOI Listing |
J Comput Chem
January 2025
Departamento de Química Fundamental, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil.
While established guidelines exist for chirality in tetrahedral molecules, there is a notable absence of clear rules for recognizing metal-centered chirality in higher-coordination complexes. We develop decision trees to assess the likelihood of chirality-at-metal in coordination complexes with coordination numbers 4-9 with mono and bidentate ligands. Using binary decision rules based on shape, ligand type, and quantity, the trees classify complexes as chiral or achiral.
View Article and Find Full Text PDFMolecules
December 2024
Xi'an Key Laboratory of Advanced Photo-Electronics Materials and Energy Conversion Device, Technological Institute of Materials & Energy Science (TIMES), Xijing University, Xi'an 710123, China.
Achieving superior circularly polarized luminescence brightness () is an important subject and continuous challenge for chiroptical materials. Herein, by applying a binary molecular design for the synthesis of chiral organo-Tb molecules, a novel pair of mononuclear chiral -pyrazolate-Tb enantiomers, [Tb(PMIP)(,-Ph-PyBox)] () and [Tb(PMIP)(,-Ph-PyBox)] (), have been synthesized and characterized. The three 1-phenyl-3-methyl-4-(isobutyryl)-5-pyrazolone () ligands play the role of efficient luminescence sensitizers and strong light-harvesting antennas, while the enantiopure 2,6-bis(4-phenyl-2-oxazolin-2-yl) pyridine ligand (/) is employed as the strong point-chiral inducer.
View Article and Find Full Text PDFNanophotonics
March 2024
Department of Materials Science and Engineering, City University of Hong Kong, Kowloon, Hong Kong, China.
Nano Lett
December 2024
School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou, Jiangsu 225002, China.
J Chromatogr B Analyt Technol Biomed Life Sci
October 2024
Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada. Electronic address:
Epoxyeicosatrienoic acids (EETs) are increasingly recognized as key metabolites in the arachidonic acid (AA) metabolic pathway. EETs are epoxy derivatives of AA with two chiral centers formed by cytochrome P450 (CYP) enzymes. EETs have reported biological activities as racemates; however, knowledge on specific optical isomers of EET is lacking.
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