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The Effects of Glucagon-Like Peptide-1 Receptor Agonists on Mitochondrial Function Within Skeletal Muscle: A Systematic Review.
J Cachexia Sarcopenia Muscle
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Department of Cardiovascular Sciences, College of Life Sciences, University of Leicester, Leicester, UK.
Background: Obesity is a chronic disease associated with increased risk of multiple metabolic and mental health-related comorbidities. Recent advances in obesity pharmacotherapy, particularly with glucagon-like peptide-1 (GLP-1) receptor agonists (RAs), have the potential to transform obesity and type 2 diabetes mellitus (T2DM) care by promoting marked weight loss, improving glycaemic control and addressing multiple obesity-related comorbidities, with added cardio-renal benefits. Dual agonists combining GLP-1 with other enteropancreatic hormones such as glucose-dependent insulinotropic polypeptide (GIP) have also been developed in recent years, leading to greater weight loss than using GLP-1 RAs alone.
View Article and Find Full Text PDFIn the vibrant linguistic landscape of Bengali, spoken by millions in Bangladesh and India, the gap between saintly and common terms is culturally and computationally significant. Recognising this, we introduce BanglaBlend, a pioneering dataset created to capture these stylistic distinctions. BanglaBlend comes with 7350 annotated sentences, 3675 in saintly form and 3675 in common form, covering a crucial need in natural language processing (NLP) resources for Bangla.
View Article and Find Full Text PDFInfluence of musical background on children's handwriting: Effects of melody and rhythm.
J Exp Child Psychol
January 2025
CLLE, University of Toulouse-Jean-Jaurès 31058 Toulouse, France.
Numerous studies have reported benefits of music listening to support learning and motor rehabilitation. In the case of handwriting, previous studies suggested that musical background improves movement speed and fluency. Whether this benefit comes from the melody or is specifically related to the rhythmic cues provided by the music remains to be established.
View Article and Find Full Text PDFThe impact of water rights reform on economic development: Evidence from city-level panel data in China.
J Environ Manage
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School of Economics, Qufu Normal University, Rizhao, 276826, China.
The water rights reform (WRR) is an important way to achieve market-oriented allocation of water resources. This article uses city-level panel data to analyze the economic effects of WRR in China. The results show that the WRR can increase overall value added by 4.
View Article and Find Full Text PDFPitfalls and perils from FDA-approved germ-line cancer predisposition tests.
Oncotarget
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The FDA approval on September 29, 2023, for "class III " blood tests to assess hereditary cancer risk make widely available tests that may be obtained through a Direct to Consumer (DTC) path. There is concern that germ-line predisposition tests may not be reimbursed by insurance adding financial burdens to individuals and families. It is generally agreed in the fields of oncology and genetics that germ-line testing for disease susceptibility including cancer is best performed under care of a healthcare provider with genetic counseling.
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