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Comparison of Ultrasound Characteristics of Peripapillary Hyperreflective Ovoid Mass-Like Structures (PHOMS) and Optic Disc Drusen in Children.
J Neuroophthalmol
January 2025
Departments of Ophthalmology (DB, G-SY, GTL, RAA) and Neurology (DB, GTL, RAA), Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania; and Division of Ophthalmology (AG, GTL, RAA), Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Background: In children, pseudopapilledema is frequently caused by peripapillary hyperreflective ovoid mass-like structures (PHOMS) or optic disc drusen (ODD). While enhanced depth imaging (EDI) OCT can identify both, lack of cooperation, especially from younger children due to the duration of testing, often necessitates the use of B-scan ultrasound (BSUS). This study investigated whether PHOMS are hyperreflective on BSUS and if BSUS can differentiate PHOMS from ODD.
View Article and Find Full Text PDFCharacterization of peripapillary hyperreflective ovoid mass-like structures (PHOMS) in a broad spectrum of neurological disorders.
Ophthalmology
December 2024
Institute of Clinical Neuroimmunology, LMU University Hospital, LMU Munich, Munich, Germany.
Objective: Peripapillary hyperreflective ovoid mass-like structures (PHOMS) have been identified in ophthalmological and neurological diseases. Since PHOMS were found more frequently in these cohorts compared to healthy controls, it is assumed that the presence of PHOMS reflects a secondary disease marker of unknown significance. The extent to which disease-specific differences are reflected in PHOMS has not yet been sufficiently investigated.
View Article and Find Full Text PDFPeripapillary hyperreflective ovoid mass-like structure (PHOMS): prevalence, risk factors, and development over time in Danish myopic children.
J AAPOS
December 2024
Department of Ophthalmology, Copenhagen University Hospital - Rigshospitalet, Glostrup, Denmark; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
Background: On optical coherence tomography (OCT) scans of the optic nerve head, peripapillary hyperreflective ovoid mass-like structures (PHOMS) are sometimes seen as a sign of axonal distension. The phenomenon has been reported more frequently in myopic subjects. We investigated PHOMS-prevalence in a myopic pediatric cohort, associated risk factors, and PHOMS development over 18 months during low-dose atropine treatment.
View Article and Find Full Text PDFIs the presence of peripapillary hyperreflective ovoid mass-like structures (PHOMS) in children related to the optic disc area, scleral canal diameter and refractive status?
Eye (Lond)
February 2025
University Hospital of Wales, Cardiff & Vale University Health Board, Cardiff, UK.
Purpose: Peripapillary hyperreflective ovoid mass-like structures (PHOMS) have been recently described on optical coherence tomography (OCT) scans of the optic nerve. We aim to determine if there is a causal relationship between OCT measurements of the optic disc area (DA), scleral canal diameter (SCD) and refractive error (spherical equivalent, SE) on the presence of PHOMS.
Methods: Retrospective analysis of OCT scans which were graded for the presence or absence of PHOMS in children with suspected papilledema was undertaken.
PHOMS: ovoid structures which are usually not egg-shaped.
Arch Soc Esp Oftalmol (Engl Ed)
December 2024
Department of Ophthalmology, University Hospital of Henares, Madrid, Spain; University Francisco de Vitoria, Madrid, Spain. Electronic address:
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