AI Article Synopsis

  • * The probe shows low limits of detection for four specific fluoroquinolones: moxifloxacin, danofloxacin, gatifloxacin, and ofloxacin, highlighting its sensitivity and selectivity.
  • * The study also introduces portable paper-based sensors that use a smartphone app for quick analysis, demonstrating the practical applications of 1-Eu in food safety.

Article Abstract

Sensitive and selective detection of fluoroquinolones, especially from different sources, is challenging. This study reported an uncommon three-cage lanthanide metal-organic framework (1-Eu) with a Eu cluster as its structural primitive using a C-symmetric 5,5-(Pyrazine-2,6-diyl) diisophthalic acid ligand. The 1-Eu probe effectively detected four fluoroquinolones through distinct color changes and spectral emission bands, demonstrating excellent performance with low detection limits: moxifloxacin (LOD: 9.3 nM), danofloxacin (LOD: 33.7 nM), gatifloxacin (LOD: 67.9 nM), and ofloxacin (LOD: 238.6 nM). Mechanistic studies revealed that internal filtration and photoinduced electron transfer (a-PET) effects were key factors. Furthermore, 1-Eu was successfully used to detect fluoroquinolones in food samples. Additionally, portable paper-based sensors were developed to quickly semi-quantify analyte concentrations using a smartphone color recognition app, underscoring the practical potential of this probe. This study introduces a novel methodology for the identification and detection of fluoroquinolones to enhance food safety.

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Source
http://dx.doi.org/10.1016/j.foodchem.2024.141652DOI Listing

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