AI Article Synopsis
- - This study focused on analyzing osteoarthritis (OA) biomarker research by reviewing the top 50 most cited articles to identify trends and research gaps.
- - The articles, published between 1999 and 2020, had a total of 6,177 citations, with a notable focus on cartilage and blood-based biomarkers while highlighting the need for more research in areas like inflammation and multi-omics.
- - The findings emphasize the absence of a universally accepted OA biomarker, indicating that further investigation into biomarkers is essential for improving OA treatment strategies and guiding future research.
Article Abstract
Purpose: This study aimed to comprehensively analyze the landscape of osteoarthritis (OA) biomarker research through the citation analysis of top-cited articles, identifying trends and gaps in this field.
Methods: The Web of Science Core Collection was utilized to retrieve the top 50 cited articles on OA biomarkers. Data extraction included publication characteristics, citation metrics, and biomarker categorization. Statistical analyses were conducted to discern correlations and assess significance.
Results: The top 50 cited articles spanned the years 1999 to 2020, and collectively cited 4849 articles, accumulating a total of 6177 citations, resulting in an average of 123.5 citations per document. Citations per article varied between 78 and 359, with a citation density ranging from 3.9 to 23.93. Analysis of the top 50 cited articles revealed comparable impact between recent and older publications. Predominant trends included cartilage-related and blood-based biomarkers, while inflammation-related, radiomics, and multi-omics emerged as potential future research directions. In BIPEDS classification, gaps were identified in biomarkers evaluating intervention efficacy and safety.
Conclusion: Despite significant advancements, there is no universally acknowledged biomarker for OA. Addressing gaps in biomarker exploration is crucial for enhancing OA management strategies. This study provides insights into prevailing trends and future research directions in OA biomarkers, guiding future investigations and therapeutic development.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11556567 | PMC |
| http://dx.doi.org/10.1177/19476035241288660 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Background: Alzheimer's disease (AD) dementia progresses from preclinical brain changes, through mild cognitive impairment (MCI), to AD with dementia. Early diagnosis and confirmation of underlying AD pathology is crucial; however, there is still much to learn about patients' diagnostic journey. We aimed to describe the diagnostic journey and barriers to diagnosis for patients with MCI or dementia due to AD in Canada.
View Article and Find Full Text PDFBibliometric Analysis of the Composition of Landmark Cerebral Venous Sinus Thrombosis Research.
Int J Cerebrovasc Dis Stroke
August 2024
Department of Neurology, Neurosurgery, & Radiology, University of Iowa Hospitals and Clinics, Iowa City, IA, United States.
Background: Cerebral Venous Sinus Thrombosis (CVST) is a relatively rare type of stroke, accounting for less than 3% of all stroke cases, and is associated with significant morbidity and mortality in young females. However, when promptly diagnosed and treated, it can have favorable outcomes. Several knowledge gaps remain regarding pathophysiology, diagnosis, and management of CVST, so critical assessment of past and present research could help close these gaps or establish targeted future research goals.
View Article and Find Full Text PDFVital pulp therapy: A bibliometric analysis of the 100 most-cited articles from 1966 to 2022.
J Conserv Dent Endod
November 2024
Department of Conservative Dentistry and Endodontics, Maulana Azad Institute of Dental Sciences, BSZ Marg, New Delhi, India.
Introduction: Vital pulp therapy (VPT) aims to preserve dental pulp after injury and has gained significant popularity due to advancements in materials and understanding of pulp biology. While bibliometric analyses are common in various fields, none have been conducted specifically for the 100 most-cited articles on VPT.
Materials And Methods: This bibliometric study analyzed the 100 most-cited VPT papers using data from Web of Science (WoS-CC), Scopus, and Google Scholar.
A Bibliometric Analysis of the 100 Top-Cited Articles on Vertical Root Fractures.
Cureus
December 2024
Department of Public Health, College of Dentistry, King Saud Bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, Ministry of National Guard Health Affairs, Riyadh, SAU.
The aim of this study was to perform a meticulous analysis and bibliometric evaluation of the top 100 most cited articles in vertical root fractures (VRFs). The bibliometric research method included 100 top-cited articles on VRFs retrieved from the Web of Science database. The key terms "vertical root fracture" OR "vertical root fractures" were used to retrieve the required dataset.
View Article and Find Full Text PDFWhy Teens Don't Talk: Understanding the Role of Stigma Within Barriers to Help Seeking.
Focus (Am Psychiatr Publ)
January 2025
The Jed Foundation, New York, New York.
The stigma of mental illness, among a larger set of barriers to help seeking, has been understudied among teens. These barriers and the sources of support were examined through an online survey with 1,428 U.S.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!