[Combined use of biomaterials and revascularisation in autoplasty of ulnar nerve].

Zh Vopr Neirokhir Im N N Burdenko

Russian Medical Academy for Continuous Professional Education, Moscow, Russia.

Published: October 2024

AI Article Synopsis

  • - Surgical treatment for peripheral nerve injuries only works effectively about 50% of the time, mainly due to issues like gaps between nerve fragments and complications from using autografts, which can lead to scar tissue and mismatch in sizes.
  • - A recent study demonstrated a successful case of multifascicular ulnar nerve autoplasty using biodegradable materials (SpheroGel and ElastoPob) and a revascularization technique that involved a connective tissue flap.
  • - Post-surgery, patients experienced significant relief from pain and ultrasound results showed successful nerve regeneration without neuroma formation, alongside positive improvements in pain and function as measured by various questionnaires.

Article Abstract

Surgical treatment of peripheral nerve injuries is effective in only 50% of cases. This is primarily due to the significant extent of the diastasis between the fragments of the damaged nerve, in which autoplasty has to be performed. The drawbacks of this technique are the formation of scar tissue, possible necrotisation of the autograft, mismatch of the donor and recipient nerve diameters. In order to overcome these drawbacks and improve the efficiency of surgical intervention, the study presents a clinical case of successful multifascicular ulnar nerve autoplasty with the use of domestic biodegradable biomaterials SpheroGel and ElastoPob, revascularization of the autograft with a connective tissue flap on a vascular pedicle. A persistent regression of local pain syndrome was observed in the early postoperative period. The effectiveness of the performed surgical intervention was confirmed by ultrasound examination: there was no evidence of neuroma in the area of the operation, regeneration of nerve bundles was noted at the site of stitching. Positive dynamics was observed in the results of VAS, DN4, DASH questionnaires.

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Source
http://dx.doi.org/10.17116/neiro20248805187DOI Listing

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