Revisiting risankizumab: a newer biologic drug in dermatology.

Ital J Dermatol Venerol

Department of Dermatology, Katihar Medical College, Al-Karim University, Katihar, India.

Published: October 2024

AI Article Synopsis

  • - Risankizumab is an FDA-approved medication for treating moderate to severe plaque psoriasis and shows promise for various other skin conditions.
  • - A thorough review of literature was conducted using databases like PubMed and Google Scholar to explore risankizumab's effectiveness in dermatology.
  • - Besides psoriasis, risankizumab has been successfully used for conditions such as hidradenitis suppurativa and pyoderma gangrenosum, and it is considered to have a good safety record.

Article Abstract

Introduction: Risankizumab is an interleukin 23p19 inhibitor, approved by the USA Food and Drug Administration (FDA) for the management of moderate to severe plaque psoriasis. Apart from its utility in psoriasis, there are a number of other dermatologic conditions where risankizumab has demonstrated value. The aim of this narrative review is to describe the utility of risankizumab in psoriasis, as well as its implication in off-label dermatologic disorders.

Evidence Acquisition: PubMed, Google Scholar, Scopus and ResearchGate were searched for scholarly articles related to risankizumab and its utility in dermatology using the search terms "Risankizumab" AND "Psoriasis" AND "other dermatological disorders."

Evidence Synthesis: Risankizumab is a valuable biologic agent for the management of psoriasis and psoriatic arthropathy. It has also been used successfully for other dermatologic disorders like hidradenitis suppurativa, pityriasis rubra pilaris and pyoderma gangrenosum.

Conclusions: Risankizumab's usage is not limited to psoriasis. Its benefit extends to many more dermatologic conditions. Besides, it has an acceptable safety profile.

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Source
http://dx.doi.org/10.23736/S2784-8671.24.07971-4DOI Listing

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