Social cognition in adults with neurofibromatosis type 1.

J Int Neuropsychol Soc

Univ Angers, Nantes Université, LPPL, SFR CONFLUENCES, Angers, France.

Published: October 2024

AI Article Synopsis

  • - The study aimed to investigate social cognition deficits in adults with neurofibromatosis type 1 (NF1) and their relation to social difficulties, comparing 20 NF1 patients with 20 healthy adults.
  • - Results showed that NF1 patients scored lower on tasks assessing emotion, theory of mind, moral reasoning, and social information processing, suggesting weak social cognition contributes to their social challenges.
  • - The study concluded that while NF1 patients exhibit social cognition weaknesses, the relationship with disease characteristics remains unclear and calls for further research with larger samples to validate these findings.

Article Abstract

Objective: Adult patients with the genetic disease neurofibromatosis type 1 (NF1) frequently report social difficulties. To date, however, only two studies have explored whether these difficulties are caused by social cognition deficits, and these yielded contradictory data. The aim of the present study was to exhaustively assess social cognition abilities (emotion, theory of mind, moral reasoning, and social information processing) in adults with NF1, compared with a control group, and to explore links between social cognition and disease characteristics (mode of inheritance, severity, and visibility).

Method: We administered a social cognition battery to 20 adults with NF1 (mean age = 26.5 years, = 7.4) and 20 healthy adults matched for sociodemographic variables.

Results: Patients scored significantly lower than controls on emotion, theory of mind, moral reasoning, and social information processing tasks. No effects of disease characteristics were found.

Conclusions: These results appear to confirm that adults with NF1 have a social cognition weaknesses that could explain, at least in part, their social difficulties, although social abilities are not all impaired to the same extent. Regarding the impact of the disease characteristics, the patient sample seemed slightly insufficient for the power analyses performed. Thus, this exploratory study should form the basis of further research, with the objective of replicating these results with larger and more appropriately matched samples.

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Source
http://dx.doi.org/10.1017/S1355617724000560DOI Listing

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