AI Article Synopsis
- Ankrd1 is a protein crucial for various biological processes, especially in heart and skeletal muscle development, as well as neurogenesis and cancer.
- The review highlights Ankrd1's involvement in multiple areas like bone formation, wound healing, and inflammation, and discusses its relevance in conditions such as cardiovascular diseases and myopathy.
- Future research is needed to further understand Ankrd1's role in diseases and explore its potential as a therapeutic target and biomarker.
Article Abstract
Ankyrin repeat domain 1 (Ankrd1) is an acute response protein that belongs to the muscle ankyrin repeat protein (MARP) family. Accumulating evidence has revealed that Ankrd1 plays a crucial role in a wide range of biological processes and diseases. This review consolidates current knowledge on Ankrd1's functions in myocardium and skeletal muscle development, neurogenesis, cancer, bone formation, angiogenesis, wound healing, fibrosis, apoptosis, inflammation, and infection. The comprehensive profile of Ankrd1 in cardiovascular diseases, myopathy, and its potential as a candidate prognostic and diagnostic biomarker are also discussed. In the future, more studies of Ankrd1 are warranted to clarify its role in diseases and assess its potential as a therapeutic target.
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Source |
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11488291 | PMC |
| http://dx.doi.org/10.1186/s11658-024-00647-w | DOI Listing |
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