Advances in the Duck Hepatitis A virus and lessons learned from those in recent years.

Microb Pathog

College of Animal Science and Technology, Shandong Agricultural University, 61 Daizong Street, Tai'an, Shandong Province, 271018, China; Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Tai'an, Shandong, 271018, China; Shandong Provincial Engineering Technology Research Center of Animal Disease Control and Prevention, Tai'an, Shandong, 271018, China. Electronic address:

Published: December 2024

AI Article Synopsis

  • Duck viral hepatitis (DVH) is a severe viral disease affecting ducklings, caused by the Duck Hepatitis A virus (DHAV), leading to neurological issues and liver damage.
  • Recent mutations and the emergence of new epidemic strains, particularly genotype 3 (DHAV-3), have complicated diagnosis and control efforts, as mixed infections increase.
  • The review focuses on various aspects of DHAV, including its biology, epidemiology, and methods for diagnosis and prevention, aiming to support future research efforts.

Article Abstract

Duckviral hepatitis (DVH) is a highly lethal and highly transmissible viral infectious disease of ducklings caused by the Duck Hepatitis A virus (DHAV), which is characterized by clinical neurological symptoms and liver enlargement with spot-like hemorrhages. In recent years, the change in diagnosis, prevention, and control of the disease has brought great challenges due to the mutation and recombination of epidemic strains, outbreaks and epidemics of genotype 3 (DHAV-3), and the rising trend of mixed infections. Here, we review DHAV on aspects of molecular biological characteristics, epidemiology, pathologic changes, pathogenesis, diagnosis, prevention, and control of the DVH to provide a scientific basis for basic and applied research in the future.

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http://dx.doi.org/10.1016/j.micpath.2024.107018DOI Listing

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