Duckviral hepatitis (DVH) is a highly lethal and highly transmissible viral infectious disease of ducklings caused by the Duck Hepatitis A virus (DHAV), which is characterized by clinical neurological symptoms and liver enlargement with spot-like hemorrhages. In recent years, the change in diagnosis, prevention, and control of the disease has brought great challenges due to the mutation and recombination of epidemic strains, outbreaks and epidemics of genotype 3 (DHAV-3), and the rising trend of mixed infections. Here, we review DHAV on aspects of molecular biological characteristics, epidemiology, pathologic changes, pathogenesis, diagnosis, prevention, and control of the DVH to provide a scientific basis for basic and applied research in the future.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.micpath.2024.107018 | DOI Listing |
Vaccines (Basel)
December 2024
Department of Avian Diseases, College of Veterinary Medicine and Center for Avian Disease, Jeonbuk National University, Iksan 54596, Republic of Korea.
Duck virus hepatitis (DVH), caused by duck hepatitis A virus (DHAV), poses significant challenges to duck farming due to high mortality rates in young ducklings. Despite the widespread use of live attenuated vaccines, the genetic diversity within DHAV strains has diminished their cross-protection efficacy. This study aimed to evaluate the cross-protective efficacy of current DHAV-1 and DHAV-3 vaccines against genetically divergent wild strains.
View Article and Find Full Text PDFMicroorganisms
November 2024
Guangxi Key Laboratory of Animal Breeding, Disease Control and Prevention, College of Animal Science and Technology, Guangxi Grass Station, Guangxi University, Nanning 530004, China.
Duck Tembusu virus (DTMUV), duck hepatitis virus (DHV), Muscovy duck reovirus (MDRV), and Muscovy duck parvovirus (MDPV) represent four emergent infectious diseases impacting waterfowl, which can be challenging to differentiate due to overlapping clinical signs. In response to this, we have developed a one-step multiplex real-time fluorescence quantitative reverse transcription PCR (qRT-PCR) assay, capable of simultaneously detecting DTMUV, DHV, MDRV, and MDPV. This method exhibits high specificity, avoiding cross-reactivity with other viruses such as Fowl adenoviruses (FADV), infectious bursal disease virus (IBDV), infectious bronchitis virus (IBV), infectious laryngotracheitis virus (ILTV), Haemophilus paragallinarum (Hpg), duck circovirus (DUCV), goose astrovirus (GoAstV), and mycoplasma gallisepticum (MG).
View Article and Find Full Text PDFVirology
December 2024
School of Life Sciences, Arizona State University, Tempe, AZ, 85287, USA; The Biodesign Center for Fundamental and Applied Microbiomics, Arizona State University, Tempe, AZ, 85287, USA; Center for Evolution and Medicine, Arizona State University, Tempe, AZ, 85287, USA; Structural Biology Research Unit, Department of Integrative, Biomedical Sciences, University of Cape Town, Observatory, Cape Town, 7925, South Africa. Electronic address:
North America is home to over 40 species of migratory waterfowl. Utilizing tissue and cloacal-swab sampling from hunter-harvested carcasses in 2021-2023, we identified circular DNA viruses associated with 116 waterfowl samples from nine species (American wigeons, Mexican ducks, northern shovelers, northern pintails, canvasbacks, mallards, American black ducks, gadwalls, and green-winged teals). We determined the genome sequences of viruses in the families Circoviridae (n = 18) and Hepadnaviridae (n = 2) from the 13 virus-infected birds.
View Article and Find Full Text PDFInt J Biol Macromol
December 2024
Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China. Electronic address:
Duck viral hepatitis (DVH) is a common and serious acute infectious disease that has a significantly impact on the duck farming industry. Duck hepatitis A virus type 3 (DHAV-3) is the major causative agent of DVH in East Asia. Host factor indicators of resistance to DHAV-3 in Pekin ducks were investigated using resistant (Z7R) and susceptible (Z7S) duck lines.
View Article and Find Full Text PDFVirus Genes
December 2024
Federal Research Center of Fundamental and Translational Medicine, Timakova Str.2, Novosibirsk, 630117, Russia.
Researchers have identified Avastrovirus as a significant genus of bird viruses, linked to various avian diseases such as enteritis, growth retardation, nephritis and hepatitis. These infections can cause substantial economic losses in agrocultureand have a widespread impact on global food production. Although there have been numerous studies on these viruses, most of them-mainly focuses on poultry.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!