Objective: Although several sealers have been developed, the zinc oxide eugenol (ZOE) sealer is still used in many private dental clinics. This study aimed to compare the biocompatibility and remineralizing capacity οf ZOE sealer with the addition of nanohydroxyapatite-tyrosine amino acid.
Methods: This study was conducted on Twenty rabbits. The rabbits were divided into four groups based on the test observation period (3, 7, 21, and 28 days) following surgical implantation. General anesthesia was administered to each rabbit, and a subcutaneous incision of approximately 1±0.5 cm was made along the symphyseal area of the mandible of each rabbit. Four bone cavities were generated in the interdental space of the lower jaw between the central and molar teeth of each rabbit, with one longitudinal subcutaneous incision. The ZOE sealers were mixed according to the manufacturer's guidelines and directly inserted within the cavities generated at the end of each test period. The animals were sacrificed, and bone biopsy was carried out at the site of testing. The biopsy samples were obtained and subjected to histological analysis using a low-power light microscope (Olympus C ⅹ 21, Japan) and immunohistochemistry using Ki67 antibody.
Results: The collected information was examined by parametric statistical tests using SPSS software version ''22." One-way ANOVA and post-hoc Duncan's tests were used to measure the significance among various groups, with statistical significance set, when "P≤0.01".
Conclusion: The 20% mixed endodontic sealer displayed excellent outcomes compared to other experimental groups, as identified by higher new bone formation at every evaluation period.
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http://dx.doi.org/10.1016/j.job.2024.09.006 | DOI Listing |
Int J Dent
January 2025
Department of Conservative Dentistry and Endodontics, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.
Due to the presence of ion reservoir, saliva may facilitate enamel remineralization and neutralize pH of acidic beverage leads to prevent enamel demineralization. Saliva substitute/artificial saliva has been developed in subsequent years and may differ in physical properties, function, or pH level from 5.0 to 7.
View Article and Find Full Text PDFAm J Dent
December 2024
Department of Restorative Sciences, Division of Operative Dentistry and Biomaterials, University of North Carolina, Adams School of Dentistry, Chapel Hill, North Carolina, USA,
Purpose: To evaluate and compare: (1) the effect of the bacterial biofilm on the dentin mineral density at the restoration-tooth interface and (2) the mineralization potential of three resin-based restorative materials (RBRM).
Methods: 16 extracted human molars free of caries and cracks were collected and stored for disinfection. Each tooth received two standardized Class II preparations with the cervical margin placed in dentin.
J Funct Biomater
December 2024
Department of Operative Dentistry, School of Dentistry, Aichi Gakuin University, Nagoya 464-8651, Japan.
This study aimed to clarify the effects of high-concentration fluoride varnish application on the inhibition of the progression of initial enamel caries. Remineralization capacity and acid resistance following high-concentration fluoride varnish application were compared with untreated models and models treated with fluoride mouthwash. Bovine enamel was used to create a model of initial enamel caries.
View Article and Find Full Text PDFWater Res
December 2024
Centre for Nature Positive Solutions, Biosciences and Food Technology Discipline, School of Science, RMIT University, Melbourne, VIC 3000, Australia.
Nutrient loading is a major driver of seagrass ecosystem decline and also threatens the capacity for seagrass ecosystems to act as 'blue carbon' sinks. Dissolved organic carbon (DOC) represents a crucial component of carbon storage in seagrass ecosystems, with refractory DOC (RDOC) playing a key role in long-term (millennial time scale) carbon stocks. The processes governing RDOC are heavily influenced by microbial activity.
View Article and Find Full Text PDFBraz Dent J
December 2024
Graduate Program in Dentistry, Federal University of Ceará, Fortaleza, Ceará, Brazil.
The aim of this study was to verify the biomodifying action of 6.5% grape seed extract solutions, with different pH, when applied on dentin collagen. Dentin bars (1.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!