Care typess is considered the cornerstone of orphan's happiness and health. In 2022, China had more than 190,000 orphans in different types of care. The purpose of the study is to examine the relationship between care types and development of orphans in China. We conducted an empirical study using cross-sectional survey data related to orphans from LZ City, Sichuan Province, China, in 2020. The data sample consists of 320 valid samples of orphans and their families, including 166 boys and 154 girls. The study conducted multiple linear regression model to analyze the relationship between care types and other family variables and the development of orphans. The results indicate that compared with other care types, grandparent care has a significant positive impact on the overall development and psychological status of orphans, with this impact being moderated by the social participation of guardians. The higher the social participation of guardians, the greater the positive impact of grandparent care on the development of orphans. Further analysis, grouped by sex and age, revealed that the effects of care types on orphan development are influenced by the gender and age of orphans. Specifically, girls and younger orphans tend to exhibit better development in a grandparent care family. The research results of this study provide an empirical basis for the government to formulate policies, and for the government, society and family to jointly ensure the better development of orphans.
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Cureus
December 2024
Neurology, Seirei Hamamatsu General Hospital, Hamamatsu, JPN.
Introduction Whole-body computed tomography angiography (CTA) may be useful during cerebral angiography and endovascular treatment (EVT), and identification of thrombi and malignant trunk tumors may be helpful in stroke typing and acute stroke care. Therefore, we aimed to assess the types and prevalence of incidental findings on whole-body CTA in this patient population. Methods This single-center, retrospective, observational study included consecutive patients with suspected acute stroke who underwent whole-body CTA in addition to brain CTA between April 2020 and August 2023.
View Article and Find Full Text PDFJACS Au
January 2025
UCIBIO-Applied Molecular Biosciences Unit, Department of Chemistry, NOVA School of Science and Technology, NOVA University Lisbon, 2829-516 Caparica, Portugal.
The mucin -glycan sialyl Tn antigen (sTn, Neu5Acα2-6GalNAcα1--Ser/Thr) is an antigen associated with different types of cancers, often linked with a higher risk of metastasis and poor prognosis. Despite efforts to develop anti-sTn antibodies with high specificity for diagnostics and immunotherapy, challenges in eliciting high-affinity antibodies for glycan structures have limited their effectiveness, leading to low titers and short protection durations. Experimental structural insights into anti-sTn antibody specificity are lacking, hindering their optimization for cancer cell recognition.
View Article and Find Full Text PDFArthroplast Today
February 2025
Levitetz Department of Orthopaedic Surgery, Cleveland Clinic Florida, Weston, FL, USA.
Background: For reimbursement purposes, current coding fails to reflect the true complexity and resource utilization of hospital encounters for surgeries performed to treat periprosthetic total hip arthroplasty (THA) infection. Therefore, when compared to aseptic revisions, we sought to determine (1) Is length of stay (LOS) longer for septic surgeries? (2) Are septic procedures more expensive? and (3) How do different surgical procedures for infection compare with aseptic revisions on hospital LOS and charges?
Methods: Retrospective chart review of 596 unilateral THA reoperations (473 patients) performed at a single institution (January 2015 to November 2020). Demographics, professional (ie, physicians), and technical (ie, room, implants) hospital charges per case were compared between 6 different surgery types: (1) aseptic revision (control; n = 364); (2) debridement, antibiotics, and implant retention (n = 11); (3) explantation (n = 145); (4) spacer exchange (n = 7); (5) 2-stage reimplantation (n = 59); and (6) 1-stage reimplantation (n = 10).
BMJ Oncol
September 2023
Department of Health Services Research & Policy, London School of Hygiene & Tropical Medicine, London, UK.
Objective: Although adjuvant trastuzumab-based treatment (TBT) improves survival for patients with HER2-positive early invasive breast cancer (EIBC), risk of toxicity grows as patient age increases. We examined use of TBT and associated severe acute toxicity event (SATE) rates to understand the real-world impact.
Methods And Analysis: Women (50+ years), newly diagnosed with HER2-positive EIBC in England, 2014-2019, were identified from Cancer Registry data, linked to the Systemic Anti-Cancer Therapy dataset for TBT information.
Front Psychol
January 2025
Department of Gastroenterology, The First People's Hospital of Yunnan Province, The Affiliated Hospital of Kunming University of Science and Technology, Kunming, Yunnan, China.
Objective: This study aimed to clarify the subgroups of career calling among Chinese nurses, explore the factors correlated with the subgroups, and investigate the relationship between nurse safety behavior and different profiles of career calling.
Methods: A cross-sectional study of 2,567 nurses from 25 hospitals in China was conducted from February to September 2023. A latent profile model of nurses' career calling was analyzed using Mplus 7.
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