First report of white piedra caused by Cutaneotrichosporon debeurmannianum.

Rev Inst Med Trop Sao Paulo

Universidade de São Paulo, Faculdade de Medicina, Instituto de Medicina Tropical de São Paulo, Laboratório de Imunologia e Micologia (LIM-53), São Paulo, São Paulo, Brazil.

Published: October 2024

AI Article Synopsis

  • Piedras are small nodules found on hair shafts, with white piedra previously linked to Trichosporon beigelii, now causing a reassessment of its causative agents.
  • The first recorded case of white piedra was identified as being caused by Cutaneotrichosporon debeurmannianum, which was studied using scanning electron microscopy and cultures from Sabouraud medium.
  • Genetic analysis showed 99.6% similarity between the nucleotide sequences of the isolated fungus and the 28S large ribosomal unit rDNA, confirming Cutaneotrichosporon debeurmannianum as the causative agent of this white piedra case.

Article Abstract

Piedras are small nodules found on the hair shafts. White piedra was initially described as caused by Trichosporon beigelii, which was later reclassified in several species. We describe the first case of white piedra caused by Cutaneotrichosporon debeurmannianum. Affected hairs were examined in natura with scanning electron microscopy, after gold metallization. The typical whitish cerebriform creamy colony was obtained in Sabouraud medium. Fungal genomic DNA extracted from cultures and locus was amplified with the NL1/NL4 primer pair from the D1/D2 region of the large ribosomal subunit (LSU) of 28S rRNA. With scanning electron microscopy, nodules are easily identified surrounding the hair shaft; with high magnifications, rounded structures adhered to each other were identified. Comparison of the nucleotide sequences of IMT-1703 Cutaneotrichosporon debeurmannianum revealed 99.6% similarity with the 28S large ribosomal unit rDNA sequence. This case of white piedra was caused by Cutaneotrichosporon debeurmannianum.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11469428PMC
http://dx.doi.org/10.1590/S1678-9946202466060DOI Listing

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