There has been increasing interest in the literature on primary thyroid diseases in guinea pigs, which are believed to be underdiagnosed. This study describes the size and characteristics of the thyroid gland on ultrasound (US) and CT examinations in the guinea pig (Cavia porcellus) without evidence of thyroid pathology and examines the possible use of US as a routine examination for thyroid diseases. This prospective and anatomical study included 20 guinea pigs that underwent CT for dental pathologies and US for thyroid gland (TG) examination. Based on US and CT images, this study evaluated the thyroid lobe dimensions (length, height, and width) and shape. Echogenicity and homogeneity were assessed on US images, and attenuation values (HU) and homogeneity were evaluated on CT images. All animals underwent CT and US examinations under anesthesia. Thyroid lobes appeared more frequently as fusiform on CT (65%) and oval on US scans (67.5%). The attenuation values on CT scans were homogeneous. On the US scans, the TG was more frequently hypoechoic. No statistically significant differences were found between the size of the right and left thyroid lobes, both with CT and US. A statistically significant difference was found between the length values on CT and US. The US and CT thyroid gland dimensions, shape, and appearance were described. Both CT and US are useful techniques for evaluating the TG in guinea pigs.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1111/vru.13455 | DOI Listing |
Front Endocrinol (Lausanne)
January 2025
Departamento de Bioquímica Clínica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.
Introduction: The sodium/iodide symporter (NIS) mediates active iodide accumulation in the thyroid follicular cell. Biallelic loss-of-function variants in the NIS-coding gene cause congenital dyshormonogenic hypothyroidism due to a defect in the accumulation of iodide, which is required for thyroid hormonogenesis.
Objective: We aimed to identify, and if so to functionally characterize, novel pathogenic gene variants in a patient diagnosed with severe congenital dyshormonogenic hypothyroidism characterized by undetectable radioiodide accumulation in a eutopic thyroid gland, as well as in the salivary glands.
J Cancer
January 2025
Department of Spinal Surgery, Tianjin Union Medical Center, Tianjin, China.
Whether autoimmune diseases caused any effects on the risk of cancers remained yet clarified. This study aimed to investigate the causal effect of autoimmune diseases on pan-cancers through mendelian randomization (MR) analysis. The GWAS summary datasets of 10 autoimmune diseases were derived from the IEU or UK biobank website.
View Article and Find Full Text PDFRev Cardiovasc Med
December 2024
Department of Cardiothoracic Surgery, The First Affiliated Hospital of Chongqing Medical University, 400016 Chongqing, China.
Introduction: Coronary atherosclerosis serves as the primary pathological etiology underlying coronary artery disease (CAD). Thyroid hormones show potential as risk factors, aside from the main standard modifiable cardiovascular risk factors (SMuRFs). This research seeks to elucidate the link between thyroid activity and coronary atherosclerosis.
View Article and Find Full Text PDFBMC Endocr Disord
December 2024
Basic and Clinical Immunology, Department of Pathology, Faculty of Medicine, University of Porto, Porto, Portugal.
Background: Hashimoto's thyroiditis (HT) is associated with high cardiovascular risk. Thyroid volume has a notable dispersion of values in these patients. This study aims to clarify the association between thyroid antibodies, thyroid morphology, insulin resistance, and lipid profile in patients with HT.
View Article and Find Full Text PDFInt J Surg Case Rep
December 2024
Department of Thyroid, Head, Neck and Maxillofacial Surgery, the Third Hospital of Mianyang, Sichuan Mental Health Center, Mianyang, Sichuan 621000, PR China. Electronic address:
Backgrounds: Parotid foreign bodies are not common. The majority of cases are caused by trauma. The clinical presentation, symptoms, and duration of discomfort vary among patients and may be challenging to treat.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!