Solid pancreatic masses: What's hidden beneath? Insights into rare pancreatic lesions.

World J Clin Cases

Department of Internal Medicine and Gastroenterology, Carol Davila University of Medicine and Pharmacy, Bucharest 020021, Romania.

Published: October 2024

AI Article Synopsis

  • The diagnostic techniques for solid pancreatic masses have improved, moving away from the assumption that all focal masses are pancreatic ductal adenocarcinoma to recognizing a variety of pancreatic lesions.
  • Advanced imaging and tissue sampling methods now allow for the identification of different conditions, including neuroendocrine tumors and rare types like metastatic clear cell sarcoma.
  • The article discusses case reports of rare pancreatic tumors diagnosed through a combination of clinical features, imaging, and endoscopic ultrasound-guided sampling, aiming to enhance understanding and management of these conditions.

Article Abstract

The diagnostic approach to solid pancreatic masses has significantly evolved from the era when a focal pancreatic mass was almost synonymous to pancreatic ductal adenocarcinoma, to a wide spectrum of pancreatic lesions, some of which have good prognosis. With the advent of advanced diagnostic tools, particularly refined imaging and tissue acquisition techniques, a broader spectrum of differential diagnoses has been recognized, encompassing conditions ranging from neuroendocrine tumors or inflammatory masses, to rare entities like metastatic clear cell sarcoma or solitary fibrous tumors. We herein discuss case reports of some rare pancreatic lesions, which were diagnosed by combining clinical and imaging features and endoscopic ultrasound-guided tissue sampling and confirmed on surgical specimens. Further reports on these rare pancreatic tumors will contribute to a better understanding of their pathogenesis and effective management.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11372521PMC
http://dx.doi.org/10.12998/wjcc.v12.i29.6255DOI Listing

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