AI Article Synopsis
- Cultivated meat (CM) aims to address the growing demand for sustainable meat by replicating the structure and toughness of natural muscle.
- The review emphasizes the importance of mechanical cues in muscle tissue organization and how the mechanical microenvironment influences the myogenesis process.
- It highlights the need for improved understanding of cell mechanics and environmental factors to enhance the texture of CM and develop sustainable biomaterials for its engineering.
Article Abstract
Cultivated meat (CM) provides a potential solution to meet the rising demand for eco-friendly meat supply systems. Recent efforts focus on producing CM that replicates the architecture and textural toughness of natural skeletal muscle. Significance of the regulated role of cellular microenvironment in myogenesis has been reinforced by the substantial influence of mechanical cues in mediating the muscle tissue organization. However, the formation of structured CM has not been adequately described in context of the mechanical microenvironment. In this review, we provide an updated understanding of the myogenesis process within mechanically dynamic three-dimensional microenvironments, discuss the effects of environmental mechanical factors on muscle tissue regeneration and how cell mechanics respond to the mechanical condition, and further highlight the role of mechanical cues as important references in constructing a sustainable Hydrocolloids-based biomaterials for CM engineering. These findings help to overcome current limitations in improving the textural properties of CM.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11481608 | PMC |
| http://dx.doi.org/10.1016/j.crfs.2024.100865 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!