The pandemic created by coronavirus disease 2019 (COVID-19) has led researchers to study to deal with this infection. The number of studies about it being performed and published is increasing over time. Due to the dramatic growth of COVID-19 scientific publications, we conducted a bibliometric and visualized study to better understand the progress, collaborations, and trend topics of COVID-19 publications in Türkiye. Material and Methods: The scientific literature on COVID-19 research in Türkiye from 2020 to 2022 was extracted from the Scopus database and analyzed using bibliometric and scientometric techniques. A total of 426.662 COVID-19-related publications were published worldwide in the 3-year period and Türkiye ranked 12th according to both publication (8.394) and case numbers (17.004.677). The most cooperations of Türkiye were with the USA, the UK, and Italy. The 5 most used keywords were determined as "COVID-19," "SARS-CoV-2," "Pandemics," "Coronavirus," and "Anxiety" respectively. It was determined by the keyword analysis that the most focused topics were related to the "COVID-19 clinic." Türkiye did not lag behind in the number of studies on her geography, and it was seen to be in the leading position compared to the Middle East countries. It is important to periodically evaluate such a large number of research articles from a broad perspective for planning and direction of future studies.
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http://dx.doi.org/10.5152/ThoracResPract.2024.24020 | DOI Listing |
PLoS Pathog
January 2025
Biotechnology and Bioengineering, Sandia National Laboratories, Livermore, California, United States of America.
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) continues to persist, demonstrating the risks posed by emerging infectious diseases to national security, public health, and the economy. Development of new vaccines and antibodies for emerging viral threats requires substantial resources and time, and traditional development platforms for vaccines and antibodies are often too slow to combat continuously evolving immunological escape variants, reducing their efficacy over time. Previously, we designed a next-generation synthetic humanized nanobody (Nb) phage display library and demonstrated that this library could be used to rapidly identify highly specific and potent neutralizing heavy chain-only antibodies (HCAbs) with prophylactic and therapeutic efficacy in vivo against the original SARS-CoV-2.
View Article and Find Full Text PDFPLoS Med
January 2025
Division of Infectious Diseases, Department of Medicine II, Medical Centre and Faculty of Medicine, Albert-Ludwigs-University, Freiburg, Germany.
Background: Self-reported health problems following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are common and often include relatively non-specific complaints such as fatigue, exertional dyspnoea, concentration or memory disturbance and sleep problems. The long-term prognosis of such post-acute sequelae of COVID-19/post-COVID-19 syndrome (PCS) is unknown, and data finding and correlating organ dysfunction and pathology with self-reported symptoms in patients with non-recovery from PCS is scarce. We wanted to describe clinical characteristics and diagnostic findings among patients with PCS persisting for >1 year and assessed risk factors for PCS persistence versus improvement.
View Article and Find Full Text PDFPLoS Med
January 2025
National Child Mortality Database, Bristol Medical School, St Michael's Hospital, University of Bristol, Bristol, United Kingdom.
Background: During the COVID-19 pandemic children and young people (CYP) mortality in England reduced to the lowest on record, but it is unclear if the mechanisms which facilitated a reduction in mortality had a longer lasting impact, and what impact the pandemic, and its social restrictions, have had on deaths with longer latencies (e.g., malignancies).
View Article and Find Full Text PDFGeriatrics (Basel)
January 2025
Department of Clinical Psychology, Psychobiology, and Methodology, Universidad de La Laguna, 38200 San Cristobal de La Laguna, Spain.
The Coronavirus disease 2019 (COVID-19) pandemic seriously threatened the health and well-being of the population. This study aims to investigate the relevance of the COVID-19 pandemic on the stress, mental distress, and well-being of older people in Spain. The design was quantitative repeated cross-sectional.
View Article and Find Full Text PDFFront Immunol
January 2025
Neuroimmunology Unit, Santa Lucia Foundation IRCCS, Rome, Italy.
Introduction: Acute COVID-19 infection causes significant alterations in the innate and adaptive immune systems. While most individuals recover naturally, some develop long COVID (LC) syndrome, marked by persistent or new symptoms weeks to months after SARS-CoV-2 infection. Despite its prevalence, there are no clinical tests to distinguish LC patients from those fully recovered.
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