AI Article Synopsis

  • The cold pressor test (CPT) is used to assess autonomic functions by inducing sympathetic activation, leading to increased blood pressure and heart rate in healthy individuals.
  • A study involving 40 healthy volunteers measured internal jugular vein (IJV) flow parameters before and after immersing their hands in cold water (1°C) for one minute.
  • Results showed significant increases in blood pressure, heart rate, and IJV volumetric flow, but a decrease in IJV diameter, indicating that CPT activates the sympathetic nervous system and affects venous flow in the IJV.

Article Abstract

BACKGROUND The cold pressor test (CPT), which has long been used to test autonomic functions by causing sympathetic excitation, increases systolic and diastolic blood pressure and heart rate and causes coronary vasodilation within physiological limits in healthy individuals. This study aimed to evaluate internal jugular vein (IJV) flow parameters using the CPT with systolic and diastolic blood pressure and heart rate in 40 healthy volunteers aged 18-40 years. MATERIAL AND METHODS The volunteers' IJV diameter, blood flow peak velocity, and volumetric flow values were recorded. Then, their right hands were immersed in a bucket of cold water maintained at 1°C up to the wrist level. At the end of the first minute (CPT-1), systolic and diastolic blood pressure, heart rhythm, IJV diameter, peak velocity, and volumetric flow measurements were performed again. RESULTS Systolic and diastolic blood pressure values were significantly higher at CPT-1 compared to baseline values (P<0.001, P<0.001). Heart rate and peak velocity values also showed a significant increase at CPT-1 compared to baseline values (P<0.001, P=0.001). While diameter values showed a significant decrease compared to baseline, volumetric flow rate values showed a significant increase at CPT-1 (P=0.003, P<0.001). CONCLUSIONS Sympathetic nervous system activation triggered by CPT increases IJV volumetric flow and flow velocity in healthy young individuals, and sympathetic nervous system activation causes a venoconstrictive effect in the IJV.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11495136PMC
http://dx.doi.org/10.12659/MSM.946055DOI Listing

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