Vascular imaging is an integral part of large-vessel vasculitis (LVV) evaluation and management. Several imaging modalities are currently employed in clinical practice including vascular ultrasound, computed tomography angiography, MRI and magnetic resonance angiography, and F-fluorodeoxyglucose PET. Well-established roles for imaging in LVV include disease diagnosis and assessment of luminal lesions reflecting vascular damage. The ability of imaging to determine treatment response, monitor disease activity, and predict future arterial damage is an area of active research.
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http://dx.doi.org/10.1016/j.rdc.2024.07.003 | DOI Listing |
Gen Thorac Cardiovasc Surg Cases
December 2024
Department of Cardiovascular Surgery, Kyushu University Hospital, 3-1-1 Maidashi, Higashi-Ku, Fukuoka, 812-8582, Japan.
Background: Takayasu arteritis is a large-vessel vasculitis, in addition to giant cell arteritis. Various post-operative complications associated with the cardiac macrovasculature have been reported. Detachment of the prosthetic valve, pseudoaneurysm formation, and dilatation of the aortic root are well-known post-operative complications associated with vasculitis syndromes, including Takayasu arteritis.
View Article and Find Full Text PDFEur Heart J Case Rep
January 2025
Department of Cardiology, Christian Medical College, New Arcot Road, Vellore 632517, India.
Background: Granulomatosis with polyangiitis (GPA) is an autoimmune multisystem disorder characterized by small vessel vasculitis with granulomatous inflammation. In this report, we describe a unique case of GPA who presented with complete heart block (CHB) and developed complications due to intracranial large vessel involvement.
Case Summary: A 47-year-old gentleman presented with CHB with a background history of arthralgia and blood-tinged nasal discharge.
Cureus
November 2024
Department of Medicine, Division of Rheumatology, Allergy and Immunology, Stony Brook University Hospital, Stony Brook, USA.
Giant cell arteritis (GCA) is a large vessel vasculitis with cranial and extracranial vessel involvement. Clinicians suspect GCA when a patient exhibits symptoms or exam findings of temporal headache with sudden vision loss, jaw or tongue claudication, scalp tenderness, abnormal temporal artery exam, and diagnostic findings, including elevated inflammatory markers. We present a case, which highlights that, despite established diagnostic measures, challenges persist.
View Article and Find Full Text PDFArthritis Res Ther
December 2024
Department of Rheumatology, Hospital Universitario de Bellvitge. Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.
Objective: To investigate differences in arterial involvement patterns on F-FDG PET-CT between predominant cranial and isolated extracranial phenotypes of giant cell arteritis (GCA).
Methods: A retrospective review of F-FDG PET-CT findings was conducted on 140 patients with confirmed GCA. The patients were divided into two groups: the cranial group, which presented craniofacial ischemic symptoms either at diagnosis or during follow-up, and the isolated extracranial group which never exhibited such manifestations.
Cureus
November 2024
Department of Internal Medicine, Northeast Georgia Medical Center Gainesville, Gainesville, USA.
Giant cell arteritis (GCA) is a medium-to-large vessel vasculitis most commonly affecting the aortic arch and carotid branches. Lingual necrosis is a rare complication of GCA caused by lingual artery vasculitis due to ischemia. A delay in diagnosis can result in irreversible complications such as tongue amputation.
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