AI Article Synopsis
- - Two cases of pseudo-signet ring cells in gastric biopsies were found in otherwise healthy adult males, highlighting a rare nonmalignant condition that can mimic cancer.
- One patient, previously treated for intestinal type gastric adenocarcinoma, underwent surgery before the condition was identified, leading to complications, while the second patient avoided surgery due to early recognition.
- The text emphasizes the importance of careful examination by experienced professionals to prevent misdiagnosis and unnecessary medical procedures when no endoscopic abnormalities are present.
Article Abstract
We describe two cases of pseudo-signet ring cells in gastric biopsies of otherwise asymptomatic adult patients. One male patient was diagnosed during follow-up of a previous intestinal type gastric adenocarcinoma and underwent surgery before recognition of this non-malignant entity. He suffered from a secondary anastomotic stenosis requiring dilatation. A second male patient was spared from surgery thanks to timely recognition by the pathologist and is still declared cancer-free until today. This extremely rare nonmalignant mimicker of cancerous signet ring cells, as seen in diffuse type gastric cancer can potentially mislead the clinician. The absence of any endoscopic abnormality should prompt a revision by an experienced pathologist, digestive oncologist and surgeon to avoid unnecessary interventions and morbidity.
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| http://dx.doi.org/10.51821/87.3.12986 | DOI Listing |
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