AI Article Synopsis
- Thyroid nodules are common and usually benign, but they can pose a risk of malignancy; this study examined the histopathological types of thyroid nodules in Ahvaz over selected years.
- The study reviewed records from 380 patients, finding that 70.3% had benign nodules while 29.7% were malignant, with papillary thyroid cancer being the most common type; significant factors related to malignancy included age, bilateral nodules, and lymphadenopathy.
- Key findings suggest that awareness of specific risk factors, such as age (30-45 years) and lymph node involvement, is crucial when assessing the likelihood of malignancy in thyroid nodules.
Article Abstract
Background: Thyroid nodule is a common finding of the endocrine system. Despite thyroid nodules in most cases being symptom-free and mostly benign, there are always malignancy risks. This study aimed to evaluate the frequency of types of thyroid nodules according to histopathology characteristics in Ahvaz hospitals.
Materials And Methods: This retrospective cross-sectional study was performed on patients with thyroid nodules with histopathological diagnosis referred to the educational hospitals of Ahvaz Jundishapur University of Medical Sciences and private endocrine clinics in Ahvaz from 2018 to 2021. Demographic characteristics, clinical history, histopathological results, ultrasonographic findings, and the presence of lymphadenopathy were collected from the patient's medical records.
Results: A total of 380 patients with thyroid nodules with a mean age of 41.2 ± 12.28 years, 79.37% of whom were female were included in the study. A total of 267 (70/3%) cases were benign. Malignancy was found in 113 (29.7%) patients in which papillary thyroid cancer was the commonest histological diagnosis ( = 99; 87.61%). Age between 30 and 45 years ( = 0.001), bilateral involvement ( = 0.028), nodules size ( = 0.004), and lymph node involvement ( < 0.0001) were significantly associated with malignancy of thyroid nodules. However, there was no significant relationship between malignancy with gender ( = 0.450), BMI ( = 0.258), and history of head and neck radiotherapy ( = 0.200). There was no significant relationship between high thyroid stimulating hormone (TSH) and the type of malignancy ( = 0.059).
Conclusion: Malignant thyroid nodules were associated with factors including age between 30 and 40 years, bilateral nodules, and lymphadenopathy. Therefore, it is important to consider these risk factors in the management and risk assessment of thyroid nodules.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11478690 | PMC |
| http://dx.doi.org/10.4103/abr.abr_158_23 | DOI Listing |
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