Investigating the complex relationship and influencing factors of frailty on nutritional status in maintenance hemodialysis patients.

Ther Apher Dial

Department of Nephrology, Institute of Kidney Diseases, West China Hospital of Sichuan University/ West China School of Nursing, Sichuan University, Chengdu, China.

Published: October 2024

Introduction: Given the high prevalence and significant challenges of frailty, a state of increased vulnerability to adverse health outcomes, among maintenance hemodialysis (MHD) patients, this cross-sectional study aimed to investigate its prevalence and explore its association with nutritional status and other relevant factors.

Methods: The study involved 290 MHD patients with an average age of 52.98 ± 13.65 years. Frailty assessments, nutritional evaluations, and medical status measurements were performed. Data analysis involved descriptive statistics, correlation analyses, and multivariate logistic regression.

Results: Among the patients, 70.3% were identified with frailty (16.9% frail, 53.4% pre-frail). Frailty was more prevalent in female patients compared to males and correlated positively with age, marital status, caregiving needs, comorbidities, dialysis duration, and higher nutritional risk scores. Negative correlations were observed with serum albumin, hemoglobin, body weight, and height.

Conclusion: A significant prevalence of frailty was found in MHD patients, with notable associations to various demographic, clinical, and nutritional factors.

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http://dx.doi.org/10.1111/1744-9987.14207DOI Listing

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