AI Article Synopsis
- The study examined risk factors for kidney issues in children with immunoglobulin A (IgA) vasculitis, focusing on a group of 117 patients aged 16 and under.
- Among the patients, 41.9% developed renal injury, with factors like age, gastrointestinal bleeding, and certain blood markers linked to this outcome.
- The final analysis identified older age, elevated D-dimer levels, and gastrointestinal bleeding as significant independent risk factors for kidney damage in these children.
Article Abstract
This study was designed to investigate the risk factors for renal involvement in children with immunoglobulin A (IgA) vasculitis. It is a hospital-based retrospective cohort study with a sample size of 117 children aged ≤16 years with primary IgA vasculitis. Out of 117 patients, 49 (41.9%) developed renal injury. Univariate analysis revealed that age, gastrointestinal bleeding (GIB), time of duration, white blood cell count, D-dimer, and platelet count were all associated with renal injury in the patients with HSP. These variables were included in the multivariate logistic regression analysis. Results showed that elevated D-dimer level, older age, and GIB were independent risk factors for renal damage in patients with IgA vasculitis. Key Words: Henoch-schonlein purpura, Immunoglobulin A vasculitis, Nephritis, D-dimer, Risk factors.
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| http://dx.doi.org/10.29271/jcpsp.2024.10.1258 | DOI Listing |
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