Early hospital readmission refers to unplanned emergency admission of patients within 30 days of discharge. Predicting early readmission risk before discharge can help to reduce the cost of readmissions for hospitals and decrease the death rate for Intensive Care Unit patients. In this paper, we propose a novel approach for prediction of unplanned hospital readmissions using discharge notes from the MIMIC-III database. This approach is based on first extracting relevant information from clinical reports using a pretrained Named Entity Recognition model called BioMedical-NER, which is built on Bidirectional Encoder Representations from Transformers architecture, with the extracted features then used to train machine learning models to predict unplanned readmissions. Our proposed approach achieves better results on clinical reports compared to the state-of-the-art methods, with an average precision of 88.4% achieved by the Gradient Boosting algorithm. In addition, explainable Artificial Intelligence techniques are applied to provide deeper comprehension of the predictive results.
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http://dx.doi.org/10.3390/diagnostics14192151 | DOI Listing |
JAMIA Open
February 2025
Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, ON M5B 1T8, Canada.
Objectives: Deidentification of personally identifiable information in free-text clinical data is fundamental to making these data broadly available for research. However, there exist gaps in the deidentification landscape with regard to the functionality and flexibility of extant tools, as well as suboptimal tradeoffs between deidentification accuracy and speed. To address these gaps and tradeoffs, we develop a new Python-based deidentification software, pyDeid.
View Article and Find Full Text PDFSci Rep
January 2025
School of Computer Science, Guangdong Polytechnic Normal University, Guangzhou, Guangdong, China.
Knowledge-aware recommendation systems often face challenges owing to sparse supervision signals and redundant entity relations, which can diminish the advantages of utilizing knowledge graphs for enhancing recommendation performance. To tackle these challenges, we propose a novel recommendation model named Dual-Intent-View Contrastive Learning network (DIVCL), inspired by recent advancements in contrastive and intent learning. DIVCL employs a dual-view representation learning approach using Graph Neural Networks (GNNs), consisting of two distinct views: a local view based on the user-item interaction graph and a global view based on the user-item-entity knowledge graph.
View Article and Find Full Text PDFPoult Sci
January 2025
Department of Animal Sciences, Faculty of Agriculture, University of Zabol, Sistan 98661-5538, Iran. Electronic address:
The availability of calcium (Ca) in poultry diets is influenced by various factors, such as the feed ingredients used. This study assessed the apparent ileal digestibility (AID) and standardized ileal digestibility (SID) of Ca in barley and soybean meal (SBM) in young quail chicks using a direct method. Three diets were formulated, including a Ca-free basal diet to evaluate ileal endogenous calcium losses (IECaL), and two diets with barley or SBM as the sole Ca sources.
View Article and Find Full Text PDFJ Am Med Inform Assoc
January 2025
Department of Biomedical Informatics, Columbia University, New York, NY 10032, United States.
Objective: Extracting PICO elements-Participants, Intervention, Comparison, and Outcomes-from clinical trial literature is essential for clinical evidence retrieval, appraisal, and synthesis. Existing approaches do not distinguish the attributes of PICO entities. This study aims to develop a named entity recognition (NER) model to extract PICO entities with fine granularities.
View Article and Find Full Text PDFBioinformatics
December 2024
School of Data Science and Society, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, United States.
Motivation: Forecasting the synergistic effects of drug combinations facilitates drug discovery and development, especially regarding cancer therapeutics. While numerous computational methods have emerged, most of them fall short in fully modeling the relationships among clinical entities including drugs, cell lines, and diseases, which hampers their ability to generalize to drug combinations involving unseen drugs. These relationships are complex and multidimensional, requiring sophisticated modeling to capture nuanced interplay that can significantly influence therapeutic efficacy.
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