AI Article Synopsis

  • Endovascular embolization, particularly using Menox, is shown to be a safe and effective treatment for cranial dural arteriovenous fistulas (DAVFs) in a study involving 19 patients over a two-year period.
  • Out of the patients treated, 68.4% achieved complete occlusion of their fistulas, with the highest success rates observed in certain anatomical locations.
  • Adverse events were rare, with only one intra-procedural issue noted, highlighting the overall safety of using Menox in these procedures.

Article Abstract

Endovascular embolization is an effective treatment option for cerebral arteriovenous malformation (AVM) and dural arteriovenous fistulas (DAVFs). The objective of this study was to assess the safety and efficacy of Menox in patients with cranial dural arteriovenous fistulas. : From January 2021 to January 2023, 19 patients with intracranial DAVFs underwent embolization procedures. All patients were treated by embolization with Menox or/and in combination with other embolization products such as Onyx (Covidien, Irvine, California), PHIL (MicroVention, Tustin, California), and Squid (Balt Extrusion, Montmorency, France). Treatment approaches were selected depending on the anatomical location of the fistula. Patients were monitored and followed-up for 12 months. : The patients' mean age was 56.26 ± 16.49 years. Of these 19 patients, 58% ( = 11) were treated with the Menox liquid embolizing agent (LEA) alone or in combination with different LEAs, while = 7 were treated with other LEAs and 1 patient was treated solely with coils. Complete occlusion of DAVFs with Menox and other agents was evident in 68.4% ( = 13/19) of patients. Complete occlusion (100%) was observed in the sinus rectus, transverse sinus, and diploic veins of the orbital roof, while complete occlusion was observed in 50% of falcotentorial patients and 60% of superior sagittal sinus patients. The lowest rate of complete fistula obliteration was observed in the dural carotid cavernous fistula (CCF) group (25%). An intra-procedural adverse event occurred in one patient. No other post-procedural adverse events were noted. Furthermore, in patients treated with Menox, total occlusion was achieved in 72.7% ( = 8) of patients, whereas the non-Menox group had 62.5% ( = 5) of patients with 100% occlusion and 37.5% ( = 3) of patients with subtotal occlusion. : Outcomes using Menox alone and in combination with other agents were effective, and it is safe for the treatment of dural arteriovenous fistulas.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11477440PMC
http://dx.doi.org/10.3390/jcm13195899DOI Listing

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