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Temperature Simulation of an Ablation Needle for the Prediction of Tissue Necrosis during Liver Ablation. | LitMetric

AI Article Synopsis

  • * A water-cooled ablation needle was tested using MWA simulations on a polyacrylamide phantom and compared with actual clinical data, focusing on necrosis assessment through the Arrhenius model and a critical temperature approach.
  • * Results showed good alignment between simulated and measured temperature increases, with some variations in predicted necrosis volume potentially due to not accounting for the heat sink effect; the overall process allows for fast simulation times, paving the way for clinical application.

Article Abstract

Microwave ablation (MWA) is the leading therapy method for treating patients with liver cancer. MWA simulation is used to further improve the therapy and to help develop new devices. A water-cooled ablation needle was reconstructed. MWA simulations of a polyacrylamide phantom were carried out and compared with a representative clinical example (tumor diameter: 8.75 mm). The Arrhenius damage model and a critical temperature approach of 60 °C were applied to assess the necrosis zones. Finally, the simulation results were compared to the corresponding MR measurements. Most of the heating in the simulation took place at a distance of 5 mm along the transverse axis and 20 mm along the longitudinal axis above the needle tip. The calculated Dice scores for the Arrhenius model were 0.77/0.53 for the phantom/clinical case. For the critical temperature approach, Dice scores of 0.60/0.66 for the phantom/clinical case were achieved. The comparison between simulated and measured temperature increases showed an excellent agreement. However, differences in the predicted necrosis volume might be caused by omitting consideration of the heat sink effect, especially in the clinical case. Nevertheless, this workflow enables short MWA simulation times (approximately 3 min) and demonstrates a step towards possible integration into daily clinical use.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11482482PMC
http://dx.doi.org/10.3390/jcm13195853DOI Listing

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