Response to the letter regarding "Differences in progressive supranuclear palsy in patients of Asian ancestry?".

Parkinsonism Relat Disord

Division of Neurology, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia; Mah Pooi Soo & Tan Chin Nam Centre for Parkinson's & Related Disorders, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

Published: January 2025

AI Article Synopsis

  • Recent studies show that progressive supranuclear palsy (PSP) is more common among South Asians, especially those with atypical symptoms.
  • The research indicates that Malaysian patients of Indian descent have a higher occurrence of PSP compared to other Asian backgrounds.
  • However, symptoms like REM sleep behavior disorder (RBD), hallucinations, and early onset do not appear to be more prevalent in Indians than in Chinese patients.*

Article Abstract

Recent studies highlight an over-representation of progressive supranuclear palsy, with atypical features, in South Asians. We offer additional insights, including an over-representation of PSP among Malaysian patients of Indian compared to other Asian ancestries. However, RBD symptoms, hallucinations, and early onset were not more frequent in Indians vs. Chinese.

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Source
http://dx.doi.org/10.1016/j.parkreldis.2024.107162DOI Listing

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