[Fluid resuscitation and application of vasoactive drugs in septic shock: timing, evaluation criteria, and specifications].

Zhonghua Jie He He Hu Xi Za Zhi

Department of Pulmonary and Critical Care Medicine, Xijing Hospital, Air Force Medical University, Xi'an 710032, China.

Published: October 2024

AI Article Synopsis

  • - Septic shock (SS) is a severe complication of sepsis, making it a critical focus in treating critically ill patients, characterized as a type of distributive shock.
  • - Standard management for SS includes fluid resuscitation and vasoactive drugs, but effective monitoring of various physiological indicators during treatment is still not clear.
  • - The authors will suggest recommendations for using fluid therapy and vasoactive drugs based on recent guidelines and literature to improve individualized and dynamic treatment strategies.

Article Abstract

Septic shock (SS), the most severe complication of sepsis, has always been a major challenge and research focus in the field of critical care treatment. SS is categorized as a distributive shock, where fluid resuscitation and the use of vasoactive drugs are the two standard measures for the clinical management of SS. However, it remains unclear how to accurately monitor macro-circulation, micro-circulation, and cellular metabolism indicators during the process of resuscitation, optimization, stabilization, and evacuation based on the dynamic pathophysiological processes of SS. This monitoring is essential to guide the comprehensive, individualized, and dynamic application of these two measures. Based on recent international management guidelines and literature review, the authors will propose relevant recommendations regarding the use of fluid therapy and vasoactive drugs.

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Source
http://dx.doi.org/10.3760/cma.j.cn112147-20240703-00380DOI Listing

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