Background: Health insurance in the United States varies in coverage of essential diagnostic tests, therapies, and specialists. Health disparities between privately and publicly insured patients with MS have not been comprehensively assessed. The objective of this study is to evaluate the impact of public versus private insurance on longitudinal brain outcomes in MS.
Methods: Lesional, thalamic, and gray and white matter volumes were extracted from longitudinal MRI of 710 MS patients. Baseline volumes and atrophy rates of lesional, thalamic, and gray and white matter volumes were compared across insurance groups.
Results: After image quality assessment, 376 (284 private / 92 public), 638 (499 / 139), and 331 (250 / 81), patients were in MS lesion, thalamic, gray and white matter analyses respectively. Baseline lesion volume was higher for publicly insured patients but increased at a slightly higher rate in those privately insured (p = 0.01). Baseline gray matter measurements were lower for patients with public insurance, but thalamic (p < 0.01) and gray matter (p < 0.01) atrophy rates were slightly higher in the private insurance group.
Conclusion: Insurance type was associated with lesion, thalamic, and gray matter volumes. The results suggest that patients with public insurance may present with more advanced disease.
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http://dx.doi.org/10.1016/j.msard.2024.105919 | DOI Listing |
J Neuroimaging
January 2025
Department of Otorhinolaryngology, School of Medicine, Kangwon National University, Chuncheon, Republic of Korea.
Background And Purpose: Tinnitus is a condition in which individuals perceive sounds, such as ringing or buzzing, without any external source. Although the exact cause is not fully understood, recent studies have indicated the involvement of nonauditory brain structures, including the limbic system. We aimed to compare the volumes of specific brain structures between patients with tinnitus and controls.
View Article and Find Full Text PDFNeuroimage
January 2025
Department of Radiology, First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.. Electronic address:
The human cerebral cortex is known for its hemispheric specialization, which underpins a variety of functions and activities. However, it is not well understood if similar lateralization exists within the deep gray matter nuclei, such as the basal ganglia (BG) and thalamus, and their associated arteries, including the lenticulostriate arteries (LSAs). To explore this, we analyzed images from 7T MRI scans of 40 healthy young individuals.
View Article and Find Full Text PDFKorean J Radiol
January 2025
Department of Radiology, Seoul National University Hospital, Seoul, Republic of Korea.
Objective: To prospectively evaluate the effect of accelerated deep learning-based reconstruction (Accel-DL) on improving brain magnetic resonance imaging (MRI) quality and reducing scan time compared to that in conventional MRI.
Materials And Methods: This study included 150 participants (51 male; mean age 57.3 ± 16.
Brain Behav
January 2025
Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Background And Objectives: Accumulation of metals quantified by quantitative susceptibility mapping (QSM) in deep gray matter (DGM) and their impact on cognition have not been studied in patients with liver cirrhosis. This study aims to use QSM to investigate the association between DGM susceptibility and cognition in cirrhotic patients.
Methods: Thirty cirrhotic patients and 30 age-, gender-, and education-matched controls were imaged using a multiecho gradient-echo sequence for QSM analysis in a 3T scanner.
Nutrients
December 2024
School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Background: Dietary intake of polyunsaturated fatty acids (PUFA) plays a significant role in the onset and progression of neurodegenerative diseases. Since the neuroprotective effects of n-3 PUFA have been widely validated, the role of n-6 PUFA remains debated, with their underlying mechanisms still not fully understood.
Methods: In this study, 169,295 participants from the UK Biobank were included to analyze the associations between dietary n-6 PUFA intake and neurodegenerative diseases using Cox regression models with full adjustments for potential confounders.
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