AI Article Synopsis
- Viral diseases have caused millions of deaths historically, making research on human-virus protein interactions crucial for developing effective control strategies.
- The increasing data on these interactions opens up new opportunities for bioinformatics research but lacks comprehensive analyses and summaries for efficient use.
- This study reviews various bioinformatic tools for examining human-virus protein interactions, aiming to provide researchers with resources to explore these interactions more effectively.
Article Abstract
Historically, there have been many outbreaks of viral diseases that have continued to claim millions of lives. Research on human-virus protein-protein interactions (PPIs) is vital to understanding the principles of human-virus relationships, providing an essential foundation for developing virus control strategies to combat diseases. The rapidly accumulating data on human-virus PPIs offer unprecedented opportunities for bioinformatics research around human-virus PPIs. However, available detailed analyses and summaries to help use these resources systematically and efficiently are lacking. Here, we comprehensively review the bioinformatic resources used in human-virus PPI research, and discuss and compare their functions, performance, and limitations. This review aims to provide researchers with a bioinformatic toolbox that will hopefully better facilitate the exploration of human-virus PPIs based on binding modes.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11658832 | PMC |
| http://dx.doi.org/10.1093/gpbjnl/qzae075 | DOI Listing |
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