Comparison of Eye-Tracking Parameters and Brain Oxygen Saturation in Patients with COVID-19 Moderate Pneumonia.

Unlabelled: The aim was to study the relationship between eye tracking (ET) parameters and cerebral tissue oxygen saturation (SctO) values in the acute period of moderate COVID-19 pneumonia.

Materials And Methods: A single-centre, non-randomised study included 92 patients in the acute period of SARS-CoV-2 moderate pneumonia (Delta variant). The mean time from admission was 1.5 ± 0.9 days. M:49, W:43. The mean age was 34.7 ± 3.9 years. The eye vergence reactivity index (VRx) was determined using a mobile ET. The cerebral oximetry was performed using Fore-Sight 2030 and included the detection of the SctO level in the frontal lobe (FLP) region. Statistical analysis was carried out using the methods of parametric statistics.

Results: The calculated vertical VRx was 0.781 ± 0.118. The calculated horizontal VRx was 0.821 ± 0.107. SctO in the FLP varied within the range from 61% to 73%. The average SctO2 values were 65.4 ± 5.2% over the left FLP and 66.2 ± 6.3% over the right FLP (p = 0.872). The regression analysis showed that HVRx and VVRx were correlated with SctO levels in both FLPs (p = 0.035 and p = 0.034, respectively, and p = 0.040 and p = 0.049, respectively).

Conclusions: Cerebral oxygen saturation in moderate pneumonia caused by the SARS-CoV-2 coronavirus has a significant destabilising effect on the oculomotor synergy (VVRx and HVRx) (p < 0.05).