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[Controversies in rhythmology].
Herzschrittmacherther Elektrophysiol
December 2024
Herz- und Diabeteszentrum Nordrhein-Westfalen, Universitätsklinik der Ruhr-Universität Bochum, Medizinische Fakultät OWL (Universität Bielefeld), Georgstr. 11, 32545, Bad Oeynhausen, Deutschland.
Prevention of cerebral thromboembolism by oral anticoagulation with dabigatran after pulmonary vein isolation for atrial fibrillation: the ODIn-AF trial.
Clin Res Cardiol
August 2024
Department of Medicine-Cardiology, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.
Background And Objectives: Long-term oral anticoagulation (OAC) following successful catheter ablation of atrial fibrillation (AF) remains controversial. Prospective data are missing. The ODIn-AF study aimed to evaluate the effect of OAC on the incidence of silent cerebral embolic events and clinically relevant cardioembolic events in patients at intermediate to high risk for embolic events, free from AF after pulmonary vein isolation (PVI).
View Article and Find Full Text PDFClinical Outcomes by Sex After Pulsed Field Ablation of Atrial Fibrillation.
JAMA Cardiol
December 2023
Helmsley Electrophysiology Center, Icahn School of Medicine at Mount Sinai, New York, New York.
Importance: Previous studies evaluating the association of patient sex with clinical outcomes using conventional thermal ablative modalities for atrial fibrillation (AF) such as radiofrequency or cryoablation are controversial due to mixed results. Pulsed field ablation (PFA) is a novel AF ablation energy modality that has demonstrated preferential myocardial tissue ablation with a unique safety profile.
Objective: To compare sex differences in patients undergoing PFA for AF in the Multinational Survey on the Methods, Efficacy, and Safety on the Postapproval Clinical Use of Pulsed Field Ablation (MANIFEST-PF) registry.
Epsilon waves: Milestones in the discovery and progress.
Ann Noninvasive Electrocardiol
November 2018
Rhythmology Unit, Cardiology Institute, Pitie Salpetriere University Hospital, Paris, France.
The Epsilon wave was first identified in 1977. Four decades of progress help people to better understand its pathological electrogenesis and diagnostic value. Currently, the Epsilon wave is on the list of the 2010 Task Force recommendations for the diagnosis of arrhythmogenic right ventricular dysplasia (ARVD).
View Article and Find Full Text PDFCurrent controversies in determining the main mechanisms of atrial fibrillation.
J Intern Med
May 2016
Department of Cardiac Electrophysiology, Heart Center, University of Leipzig, Leipzig, Germany.
Despite considerable basic research into the mechanisms of atrial fibrillation (AF), not much progress has been made in the prognosis of patients with AF. With the exception of anticoagulant therapy, current treatments for AF still do not improve major cardiovascular outcomes. This may be due partly to the diverse aetiology of AF with increasingly more factors found to contribute to the arrhythmia.
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