Insomnia, OSA, and Mood Disorders: The Gut Connection.

Curr Psychiatry Rep

Department of Pharmaceutical Biosciences, Uppsala University, Husargatan 3, Uppsala, 751 24, Sweden.

Published: December 2024

AI Article Synopsis

  • The review focuses on the connection between sleep disorders like insomnia and obstructive sleep apnea (OSA) and the gut microbiome, summarizing significant findings in this research area.
  • Research indicates a complex relationship between gut microbiome imbalances and sleep issues, suggesting that they may affect each other, with certain gut species linked to sleep and mood variations in conditions like depression.
  • Further research is necessary to explore the gut microbiome as a potential treatment for insomnia, while also emphasizing the need for standardized methods in future studies.

Article Abstract

Purpose Of Review: With the growing body of research examining the link between sleep disorders, including insomnia and obstructive sleep apnea (OSA), and the gut microbiome, this review seeks to offer a thorough overview of the most significant findings in this emerging field.

Recent Findings: Current evidence suggests a complex association between imbalances in the gut microbiome, insomnia, and OSA, with potential reciprocal interactions that may influence each other. Notably, specific gut microbiome species, whether over- or under-abundant, have been associated with variation in both sleep and mood in patients diagnosed with, e.g., major depressive disorder or bipolar disorder. Further studies are needed to explore the potential of targeting the gut microbiome as a therapeutic approach for insomnia and its possible effects on mood. The variability in current scientific literature highlights the importance of establishing standardized research methodologies.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11706850PMC
http://dx.doi.org/10.1007/s11920-024-01546-9DOI Listing

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