Various healthcare domains have witnessed successful preliminary implementation of artificial intelligence (AI) solutions, including radiology, though limited generalizability hinders their widespread adoption. Currently, most research groups and industry have limited access to the data needed for external validation studies. The creation and accessibility of benchmark datasets to validate such solutions represents a critical step towards generalizability, for which an array of aspects ranging from preprocessing to regulatory issues and biostatistical principles come into play. In this article, the authors provide recommendations for the creation of benchmark datasets in radiology, explain current limitations in this realm, and explore potential new approaches. CLINICAL RELEVANCE STATEMENT: Benchmark datasets, facilitating validation of AI software performance can contribute to the adoption of AI in clinical practice. KEY POINTS: Benchmark datasets are essential for the validation of AI software performance. Factors like image quality and representativeness of cases should be considered. Benchmark datasets can help adoption by increasing the trustworthiness and robustness of AI.
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http://dx.doi.org/10.1186/s13244-024-01833-2 | DOI Listing |
PLoS One
January 2025
School of Information Science and Engineering, Xinjiang University, Urumqi, China.
Anomaly detection is crucial in areas such as financial fraud identification, cybersecurity defense, and health monitoring, as it directly affects the accuracy and security of decision-making. Existing generative adversarial nets (GANs)-based anomaly detection methods overlook the importance of local density, limiting their effectiveness in detecting anomaly objects in complex data distributions. To address this challenge, we introduce a generative adversarial local density-based anomaly detection (GALD) method, which combines the data distribution modeling capabilities of GANs with local synthetic density analysis.
View Article and Find Full Text PDFPLoS One
January 2025
Department of Computer Science, GC Women University Sialkot, Sialkot, Pakistan.
Modern dialogue systems rely on emotion recognition in conversation (ERC) as a core element enabling empathetic and human-like interactions. However, the weak correlation between emotions and semantics poses significant challenges to emotion recognition in dialogue. Semantically similar utterances can express different types of emotions, depending on the context or speaker.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
January 2025
Guangdong Institute of Intelligence Science and Technology, 519031 Hengqin, Zhuhai, Guangdong, China.
Manifold learning techniques have emerged as crucial tools for uncovering latent patterns in high-dimensional single-cell data. However, most existing dimensionality reduction methods primarily rely on 2D visualization, which can distort true data relationships and fail to extract reliable biological information. Here, we present DTNE (diffusive topology neighbor embedding), a dimensionality reduction framework that faithfully approximates manifold distance to enhance cellular relationships and dynamics.
View Article and Find Full Text PDFBrain
January 2025
State Key Laboratory of Cardiology and Medical Innovation Center, Shanghai East Hospital, Clinical Center for Brain and Spinal Cord Research, School of Medicine, Tongji University, 200331, Shanghai, China.
Amyotrophic lateral sclerosis (ALS) is a severe motor neuron disease, with most sporadic cases lacking clear genetic causes. Abnormal pre-mRNA splicing is a fundamental mechanism in neurodegenerative diseases. For example, TAR DNA-binding protein 43 (TDP-43) loss-of-function (LOF) causes widespread RNA mis-splicing events in ALS.
View Article and Find Full Text PDFJ Imaging
January 2025
RCAM Laboratory, Telecommunications Department, Sidi Bel Abbes University, Sidi Bel Abbes 22000, Algeria.
In recent years, deep-network-based hashing has gained prominence in image retrieval for its ability to generate compact and efficient binary representations. However, most existing methods predominantly focus on high-level semantic features extracted from the final layers of networks, often neglecting structural details that are crucial for capturing spatial relationships within images. Achieving a balance between preserving structural information and maximizing retrieval accuracy is the key to effective image hashing and retrieval.
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