Intestinal ligation during ovariohysterectomy has not been previously reported in dogs. Risk factors for this complication appear to be the same as those for ureteral injury, namely decreased surgical visualization due to small patient size and small incision size. This case report describes how the presentation of intestinal ligation in a 2-kg, 11-month-old chihuahua can mimic that of iatrogenic ureteral injury with vomiting, anorexia, and severe azotemia. Ultrasound served as a key diagnostic to visualize intestinal mechanical obstruction, an encircling ligature around a segment of jejunum with no blood flow on Doppler interrogation, and normal appearance and blood flow of the ureters and kidneys. The treatment consisted of aggressive fluid therapy, circulatory support, and emergent resection and anastomosis of the necrotic portion of the intestines. Within 48 h, the dog's azotemia was resolved, and it was reported to be doing well at 1-month follow-up.
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http://dx.doi.org/10.1155/2024/8550288 | DOI Listing |
Int J Nanomedicine
January 2025
Affiliated Hospital, Qinghai University, Xining, Qinghai, People's Republic of China.
Background: Acacetin (AC) is a flavonoid compound with antiperoxidant, anti-inflammatory, and antiplasmodial activity. However, the solubility of AC is poor and nano acacetin (Nano AC) was synthesized. The intestinal mucosal barrier is impaired in sepsis rats, and the protective effects and mechanism of AC and Nano AC on the intestinal mucosal barrier are unclear.
View Article and Find Full Text PDFTech Coloproctol
December 2024
Colorectal Surgery, Champalimaud Foundation, Av. Brasilia, 1400-038, Lisbon, Portugal.
Aim: The use of robotic surgery is increasing significantly. Specific training is fundamental to achieve high quality and better oncological outcomes. This work defines key exposure techniques in robotic total mesorectal excision (TME).
View Article and Find Full Text PDFJ Vasc Surg Venous Lymphat Disord
December 2024
Division of Vascular Surgery, UPMC, Pittsburgh, Pennsylvania; Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania. Electronic address:
Background: Portal venous system aneurysms (PVA) are increasingly diagnosed on cross-sectional computed tomography (CT) imaging. However, the natural history of these aneurysms is poorly understood and reports are limited to small case series.
Methods: Terms relevant to PVA were searched in radiology reports (2010-2022) with PVA presence confirmed by manual review.
Mol Biotechnol
December 2024
Department of Intensive Care Unit, The Third Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, 310000, Zhejiang, China.
This study aimed to investigate the protective effects of Lycium barbarum polysaccharide (LBP) on digestive function and intestinal barrier integrity in septic mice, and to explore its underlying mechanisms. A total of 70 healthy male BALB/C mice were randomly assigned into five groups: blank control group (BG, n = 12), control group (CG, n = 12), low-dose group (LDG, n = 12, 200 mg/kg), medium-dose group (MDG, n = 12, 400 mg/kg), and high-dose group (HDG, n = 12, 800 mg/kg). A sepsis model was established by cecal ligation and puncture, followed by treatment with different doses of LBP.
View Article and Find Full Text PDFInt J Biol Macromol
December 2024
School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China; National Grain Industry (Urban Grain and Oil Security) Technology Innovation Center, Shanghai 200093, China. Electronic address:
Oral delivery of macromolecular drugs is often hampered by the harsh gastrointestinal environment, which makes the drugs have poor bioavailability. Insulin, the most used drug for diabetes, also faces the same challenge for oral administration. Hence, we decorated microbial metabolite propionate on chitosan (CS) to fabricate insulin-loaded propionate-modified CS hydrogel nanoparticles (IN-CS/PA HNPs).
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