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Histopathological and immunohistochemical analysis of a suspected extraskeletal osteosarcoma in a rabbit (). | LitMetric

AI Article Synopsis

  • An 8-year-old male rabbit had a large subcutaneous mass on its fourth digit, characterized by ulceration and necrosis, measuring 5.5 x 3.5 x 5.2 cm.
  • Imaging showed no bone involvement, and the mass was partially removed followed by electrochemotherapy.
  • Histopathological tests identified the mass as extraskeletal osteosarcoma (ESOS) through specific markers, outlining the rabbit's clinical presentation and treatment options.

Article Abstract

An 8-year-old male rabbit () presented with a subcutaneous mass in the proximal region of the fourth and accessory digit measuring 5.5 x 3.5 x 5.2cm. The mass was non-alopecic and exhibited irregular surface, ulceration and necrosis with predominantly pale and light brown coloring. Radiography revealed no involvement of bone and adjacent periosteum. The mass was marginally resected and the electrochemotherapy (ECT) was performed on the surgical bed. Histopathology and immunohistochemical analysis revealed positive reactions for Vimentin, Runx-2 and ki-67, leading to a diagnosis of extraskeletal osteosarcoma (ESOS). This report described a case of ESOS in a rabbit, thereby delineating its clinical presentation, anatomopathological characteristics, diagnostic modalities and recommended therapeutic interventions.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11469577PMC
http://dx.doi.org/10.29374/2527-2179.bjvm003324DOI Listing

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