Background: The term Ponticulus Posticus (PP) refers to a complete or partial bony bridge on the vertebral artery that passes through the superior-lateral surface of the posterior arch of the atlas. This study was conducted with the aim of investigating the prevalence of ponticulus posticus in orthodontic patients referred to Mashhad Dental School.
Methods: In this cross-sectional study, one thousand cephalograms were selected from the patients referred to the orthodontics department of Mashhad Dental School between 2017 and 2021. In lateral cephalogram images with appropriate quality, the type of malocclusion was determined using the AudaxCeph software (Audax d.o.o., Ljubljana, Slovenia). Then, the images were evaluated for the presence or absence of PP. For the statistical analysis, chi-square and t-test were used.
Results: In this study, 861 lateral digital cephalograms were analyzed. The overall prevalence of PP in the studied population was 17.5%. The prevalence of PP was higher in males than in females ( < 0.001). The variables "presence of PP" ( = 0.056) and "type of PP" ( = 0.522) were found to be independent of age groups. Although class II subjects showed a higher prevalence of PP, skeletal malocclusion classes were not found to be correlated with the presence of PP ( = 0.104) nor with its types ( = 0.958).
Conclusion: The current study is considered the primary study that provides data concerning the prevalence of PP in the East of Iran. Our study showed that PP was not rare in this region. More studies with 3D radiological examination are needed to increase the accuracy of diagnosing PP and its prevalence in Iran.
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http://dx.doi.org/10.47176/mjiri.38.75 | DOI Listing |
Cureus
November 2024
Department of Orthopedic Surgery, Fukushima Medical University School of Medicine, Fukushima, JPN.
This study reports two cases of upper cervical myelopathy with athetoid cerebral palsy (ACP) treated with posterior arch resection. Both patients exhibited good long-term outcomes with no recurrence at five or 10 years. Decompression surgery can be effective for ACP patients with upper cervical spine lesions.
View Article and Find Full Text PDFBiol Direct
December 2024
Oncology Department of Integrated Traditional Chinese and Western Medicine, First Affiliated Hospital of Anhui Medical University, Hefei, China.
Background: UCHL5 was initially recognized as a multifunctional molecule. While recent research has highlighted its involvement in tumor malignant biological behaviors, its specific role in promoting tumor cell apoptosis has drawn particular attention. However, the precise relationship between UCHL5 and various tumor types, as well as its influence within the immune microenvironment, remains unclear.
View Article and Find Full Text PDFSurg Radiol Anat
December 2024
Department of Anatomy, Faculty of Medicine, Sivas Cumhuriyet University, Sivas, 58140, Turkey.
Purpose: The paracondylar process (PCP) is defined as the bony prominence extending from the outer side of the condyles on the outer surface of the occipital bone downwards towards the transverse process of the atlas (TPA). In this case report, the morphometry of the rarely seen PCP and its morphometric data with neighboring structures are evaluated.
Case Report And Results: Unilateral (right-sided) PCP was observed in the cranium of a Caucasian female.
World Neurosurg
December 2024
Department of Neurological Surgery, The University of Pittsburgh Medical Center, Pittsburgh, PA, United States.
Background: Simultaneous fractures of C1 and C2 are increasingly common, but contemporary series are limited in their evaluation.
Methods: All patients with traumatic fractures of both C1 and C2 admitted to an academic trauma center from 2012 to 2022 were retrospectively analyzed. Multivariable regression was used to identify characteristics relevant to management and outcomes.
Am J Transl Res
November 2024
Department of General Practice, Pingjiang New Town Community Health Service Center Sujin Street, Gusu District, Suzhou 215000, Jiangsu, China.
Background: Cancer represents a highly intricate disease, characterized by the uncontrolled proliferation and invasion of aberrant cells, leading to widespread global morbidity and mortality. This study investigates the influence of CD19, a marker specific to B-cells, within the tumor microenvironment (TME) across a spectrum of cancer types.
Methodology: To explore the role of CD19, we employed a wide array of bioinformatics tools and databases, including UALCAN, GEPIA2, univariate Cox regression, KM plotter, HPA, GSCA, cBioPortal, TISIDB, and DAVID.
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