Problems: Plant diseases significantly impact crop growth and yield. The variability and unpredictability of symptoms postinfection increase the complexity of image-based disease detection methods, leading to a higher false alarm rate.
Aim: To address this challenge, we have developed an efficient, weakly supervised agricultural disease localization model using Siamese neural networks.
Methods: This model innovatively employs a Siamese network structure with a weight-sharing mechanism to effectively capture the visual differences in plants affected by diseases. Combined with our proprietary Agricultural Disease Precise Localization Class Activation Mapping algorithm (ADPL-CAM), the model can accurately identify areas affected by diseases, achieving effective localization of plant diseases.
Results And Conclusion: The results showed that ADPL-CAM performed the best on all network architectures. On ResNet50, ADPL-CAM's top-1 accuracy was 3.96% higher than GradCAM and 2.77% higher than SmoothCAM; the average Intersection over Union (IoU) is 27.09% higher than GradCAM and 19.63% higher than SmoothCAM. Under the SPDNet architecture, ADPL-CAM achieves a top-1 accuracy of 54.29% and an average IoU of 67.5%, outperforming other CAM methods in all metrics. It can accurately and promptly identify and locate diseased leaves in crops.
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http://dx.doi.org/10.3389/fpls.2024.1418201 | DOI Listing |
Front Oncol
December 2024
Department of Hepatobiliary and Pancreatic Surgery, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Zhengzhou, Henan, China.
Background And Aims: The levels of M2 macrophages are significantly associated with the prognosis of hepatocellular carcinoma (HCC), however, current detection methods in clinical settings remain challenging. Our study aims to develop a weakly supervised artificial intelligence model using globally labeled histological images, to predict M2 macrophage levels and forecast the prognosis of HCC patients by integrating clinical features.
Methods: CIBERSORTx was used to calculate M2 macrophage abundance.
Cancer Lett
January 2025
Department of Radiology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, P.R. China, 210029; The Affiliated Suqian First People's Hospital of Nanjing Medical University, Suqian, Jiangsu Province, China. Electronic address:
Preoperative detection of muscle-invasive bladder cancer (MIBC) remains a great challenge in practice. We aimed to develop and validate a deep Vesical Imaging Network (ViNet) model for the detection of MIBC using high-resolution Tweighted MR imaging (hrTWI) in a multicenter cohort. ViNet was designed using a modified 3D ResNet, in which, the encoder layers were pretrained using a self-supervised foundation model on over 40,000 cross-modal imaging datasets for transfer learning, and the classification modules were weakly supervised by an experiential knowledge-domain mask indicated by a nnUNet segmentation model.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Neurosurgery, West China Hospital, Sichuan University, 37 Guoxue Avenue, Chengdu, 610041, People's Republic of China.
Multiple artificial intelligence systems have been created to facilitate accurate and prompt histopathological diagnosis of tumors using hematoxylin-eosin-stained slides. We aimed to investigate whether weakly supervised deep learning can aid in glioma diagnosis. We analyzed 472 whole slide images (WSIs) from 226 patients in West China Hospital (WCH) and 1604 WSIs from 880 patients in The Cancer Genome Atlas (TCGA).
View Article and Find Full Text PDFJAMIA Open
February 2025
Hasso Plattner Institute for Digital Engineering, University of Potsdam, Potsdam 14482, Germany.
Objective: To improve performance of medical entity normalization across many languages, especially when fewer language resources are available compared to English.
Materials And Methods: We propose xMEN, a modular system for cross-lingual (x) medical entity normalization (MEN), accommodating both low- and high-resource scenarios. To account for the scarcity of aliases for many target languages and terminologies, we leverage multilingual aliases via cross-lingual candidate generation.
Am J Pathol
December 2024
Department of Computer Science, Faculty of Engineering Sciences, University College London, London, United Kingdom.
Understanding the tumor hypoxic microenvironment is crucial for grasping tumor biology, clinical progression, and treatment responses. This study presents a novel application of artificial intelligence in computational histopathology to evaluate hypoxia in breast cancer. Weakly supervised deep learning models can accurately detect morphologic changes associated with hypoxia in routine hematoxylin and eosin (H&E)-stained whole slide images (WSIs).
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