Introduction Asthma is one of the serious health problems among children, accounting for a major proportion of lost school days due to absenteeism, decreased academic performances, and lesser social interactions. It can impair a child's activities like playing sports and also their sleeping pattern with frequent school absenteeism. In South India, only a few school-based studies to determine the prevalence of asthma have been carried out, and even fewer studies are done in community settings in rural areas of Tamil Nadu. Hence, this community-based study was done to find out the prevalence of asthma among children aged 5-10 years in rural areas of Coimbatore, Tamil Nadu. Aim & objective To estimate the prevalence of asthma among children aged 5-10 years in rural areas of Coimbatore, Tamil Nadu. Materials and methods A community-based cross-sectional study was conducted in rural areas of Coimbatore, Tamil Nadu. A sample of 726 children from the randomly selected seven villages were studied. The sample size was calculated for a finite population. The standardized International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire and calibrated instruments were used as data collection tools. Ethical approval was obtained. Data entry was done in Microsoft Excel and analyzed using the SPSS 19.0 version. The "t" test was used to compare the mean difference between the quantitative variables and the chi-square test was used to test the association between categorical variables. P-value <0.05 was considered as statistically significant. Results The overall prevalence of self-reported asthma was 5.1%. Boys had 1.7 times higher prevalence compared to girls. The prevalence of possible or suspected cases of asthma using the ISAAC screening questionnaire was 20.9%. In univariate analysis, the risk of having asthma among children is significantly higher among those with a positive family history of asthma. Conclusion The study found that the prevalence of self-reported asthma in rural settings is low (5.1%). However, our study also identifies a large number of children (20.9%) with symptoms suggestive of asthma using the ISAAC questionnaire that need the attention of a specialist for early diagnosis and care for reducing morbidity and episode severity.
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http://dx.doi.org/10.7759/cureus.69329 | DOI Listing |
Can Assoc Radiol J
January 2025
Department of Radiology, Dalhousie University, Halifax, NS, Canada.
Contrast media, including iodinated contrast media and gadolinium-based contrast agents, are commonly administered pharmaceuticals with excellent safety profiles. However, a minority of the population may experience a hypersensitivity reaction following intravenous administration. Hypersensitivity reactions can be immediate or delayed, and range from mild, such as urticaria, to severe, including anaphylaxis.
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December 2024
Inmunotek SL Laboratories, 28000 Madrid, Spain.
Climate change is significantly altering the dynamics of airborne allergens, affecting their seasonality, allergenicity, and geographic distribution, which correlates with increasing rates of allergic diseases. This study investigates aeroallergen sensitization among populations from Tenerife, Spain, and Lima, Peru-two regions with similar climates but distinct socio-economic conditions. Our findings reveal that Spanish individuals, particularly those with asthma, demonstrate higher sensitization levels to a broader range of allergens, especially mites, with 85% of participants reacting to at least one mite allergen.
View Article and Find Full Text PDFPolymers (Basel)
December 2024
Department of Zoology, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.
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January 2025
Department of Public Health Studies, Elon University, Elon, NC, USA.
Background: The increasing prevalence of type 2 diabetes mellitus (T2DM) in lower and middle - income countries call for preventive public health interventions. Studies from Africa including those from Ghana, consistently reveal high T2DM-related mortality rates. While previous research in the Ho municipality has primarily examined risk factors, comorbidity, and quality of life of T2DM patients, this study specifically investigated mortality predictors among these patients.
View Article and Find Full Text PDFCommun Biol
January 2025
Institute for Stroke and Dementia Research (ISD), LMU University Hospital, LMU Munich, Munich, Germany.
Circulating cytokines orchestrate immune reactions and are promising drug targets for immune-mediated and inflammatory diseases. Exploring the genetic architecture of circulating cytokine levels could yield key insights into causal mediators of human disease. Here, we performed genome-wide association studies (GWAS) for 40 circulating cytokines in meta-analyses of 74,783 individuals.
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